Detailed information of TA system TA090071

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): hok-sok/-
• Location: 3718067..3718324
• Replicon: chromosome
• Accession: NZ_CP025317
• Organism: Escherichia albertii strain 1551-2

Toxin (Protein)

• Gene name: hokA
• Uniprot ID: A0A8D9PLG9
• Locus tag: CXP54_RS18985
• Protein ID: WP_069913754.1
• Coordinates: 3718067..3718219 (-)
• Length: 51 a.a.

Antitoxin (RNA)

Gene name	sokA
Locus tag	-
Coordinates	3718276..3718324 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CXP54_RS18960	3714171..3714830	+	660	WP_000747625.1	OmpA family lipoprotein	-
CXP54_RS18965	3714934..3715908	+	975	WP_000804993.1	glyoxylate/hydroxypyruvate reductase GhrB	-
CXP54_RS18970	3715961..3716671	-	711	WP_002460072.1	DUF3053 domain-containing protein	-
CXP54_RS18975	3717094..3717384	+	291	WP_000455794.1	HTH-type transcriptional regulator	-
CXP54_RS18980	3717667..3717879	+	213	WP_000014594.1	RNA chaperone/antiterminator CspA	-
CXP54_RS18985	3718067..3718219	-	153	WP_069913754.1	type I toxin-antitoxin system toxin HokA	Toxin
-	3718276..3718324	+	49	-	-	Antitoxin
CXP54_RS18990	3718542..3720611	-	2070	WP_103054034.1	glycine--tRNA ligase subunit beta	-
CXP54_RS18995	3720621..3721532	-	912	WP_001168544.1	glycine--tRNA ligase subunit alpha	-
CXP54_RS19000	3721628..3721927	-	300	WP_000979961.1	YsaB family lipoprotein	-
CXP54_RS19005	3722100..3723095	+	996	WP_103054035.1	acyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Hok/gef cell toxic protein (5-46)

Sequences

Toxin

Protein

• Length: 51 a.a.
• Molecular weight: 5940.19 Da
• Isoelectric Point: 7.7173

>T90071 WP_069913754.1 NZ_CP025317:c3718219-3718067 [Escherichia albertii]
MPQKYRLLSLIVICFTLLFFTWMIRDSLCELHIKQGSYELAVFLACNLKE

Nucleotide

• Length: 153 bp

>T90071 NZ_CP025317:c3718219-3718067 [Escherichia albertii]
ATGCCGCAGAAATATAGATTGCTTTCTTTAATAGTGATTTGTTTCACGCTTTTATTTTTCACCTGGATGATAAGGGATTC
ACTGTGTGAATTGCATATTAAACAGGGGAGTTATGAGCTGGCGGTGTTTTTAGCCTGCAATTTGAAAGAGTAA

Antitoxin

Nucleotide

• Length: 49 bp

>AT90071 NZ_CP025317:3718276-3718324 [Escherichia albertii]
GCATAGAGGGGCCTCACTTTGATTTATAGTCAGGTGGGGCTTTTCTCTG

Structures

Antitoxin