Detailed information of TA system TA090047

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): higBA (relBE)/-
• Location: 4349300..4349954
• Replicon: chromosome
• Accession: NZ_CP025309
• Organism: Pseudomonas chlororaphis strain Lzh-T5

Toxin (Protein)

• Gene name: higB
• Uniprot ID: -
• Locus tag: CXP47_RS19225
• Protein ID: WP_101284187.1
• Coordinates: 4349300..4349650 (+)
• Length: 117 a.a.

Antitoxin (Protein)

• Gene name: higA
• Uniprot ID: -
• Locus tag: CXP47_RS19230
• Protein ID: WP_009049793.1
• Coordinates: 4349640..4349954 (+)
• Length: 105 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CXP47_RS19215	4346050..4347582	+	1533	WP_009049790.1	NADH-quinone oxidoreductase subunit M	-
CXP47_RS19220	4347590..4349053	+	1464	WP_009049791.1	NADH-quinone oxidoreductase subunit NuoN	-
CXP47_RS19225	4349300..4349650	+	351	WP_101284187.1	toxin	Toxin
CXP47_RS19230	4349640..4349954	+	315	WP_009049793.1	transcriptional regulator	Antitoxin
CXP47_RS19235	4350121..4351863	-	1743	WP_023964376.1	ABC transporter substrate-binding protein	-
CXP47_RS19245	4352027..4352299	-	273	WP_009049795.1	DUF2160 domain-containing protein	-
CXP47_RS19250	4352310..4353110	-	801	WP_007929618.1	carbohydrate ABC transporter permease	-
CXP47_RS19255	4353122..4353988	-	867	WP_009049796.1	sugar ABC transporter permease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Cro/C1-type helix-turn-helix domain (41-100)

Sequences

Toxin

Protein

• Length: 117 a.a.
• Molecular weight: 13812.81 Da
• Isoelectric Point: 8.5032

>T90047 WP_101284187.1 NZ_CP025309:4349300-4349650 [Pseudomonas chlororaphis]
MDALFIELPPFQRHRQDYLDDELFRSLQLELLKAPEAGDLIEGTDGLRKIRFVDERRHKGKRGGIRVIYYWWSGGAQLWL
FTLYAKNELNDLTPHQKKLLKQLLNREVEARTHHET

Nucleotide

• Length: 351 bp

>T90047 NZ_CP025309:4349300-4349650 [Pseudomonas chlororaphis]
ATGGACGCACTTTTTATTGAGCTGCCCCCGTTCCAACGCCATCGACAGGACTACCTGGACGACGAGCTTTTTCGTAGCTT
GCAGCTTGAGTTGCTGAAAGCCCCCGAAGCCGGAGATCTCATCGAGGGAACCGATGGCTTGCGCAAGATCCGCTTTGTCG
ATGAGCGACGGCACAAGGGCAAACGCGGCGGGATCCGGGTGATTTATTACTGGTGGTCCGGAGGCGCCCAACTCTGGCTC
TTCACCCTTTACGCAAAGAACGAGCTGAACGACCTGACACCCCATCAGAAAAAACTGCTCAAGCAACTGCTGAACAGAGA
AGTCGAGGCGAGAACCCATCATGAAACGTGA

Antitoxin

Protein

• Length: 105 a.a.
• Molecular weight: 11917.85 Da
• Isoelectric Point: 10.6052

>AT90047 WP_009049793.1 NZ_CP025309:4349640-4349954 [Pseudomonas chlororaphis]
MKRDIFSELVEGFDALAKERQGKLTLRTYKVKLNALLPITAEEVLAVREQLNLSRSVFAMYLRTNTRTLENWEQGRAKPN
AQATTLIRLVQRFPDTVERLAALA

Nucleotide

• Length: 315 bp

>AT90047 NZ_CP025309:4349640-4349954 [Pseudomonas chlororaphis]
ATGAAACGTGACATCTTTTCCGAACTGGTCGAAGGTTTCGACGCCCTGGCCAAAGAGCGCCAAGGCAAGCTCACGCTGCG
CACCTACAAGGTCAAGCTGAACGCGCTGCTCCCGATCACCGCTGAAGAAGTGCTGGCCGTGCGCGAGCAGTTGAACCTGT
CCAGATCGGTATTTGCCATGTACCTGCGCACCAATACTCGGACCCTGGAGAACTGGGAGCAAGGACGGGCAAAACCCAAC
GCTCAGGCCACTACCCTGATCCGCCTGGTACAGCGTTTTCCCGATACGGTGGAGCGGCTGGCAGCATTGGCCTGA