Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/COG4683-HTH_37 |
| Location | 66791..67448 | Replicon | plasmid pSNE2-1923 |
| Accession | NZ_CP025275 | ||
| Organism | Salmonella enterica subsp. enterica serovar Newport str. USDA-ARS-USMARC-1923 | ||
Toxin (Protein)
| Gene name | higB | Uniprot ID | U3PDC3 |
| Locus tag | AW79_RS25175 | Protein ID | WP_000270043.1 |
| Coordinates | 66791..67141 (+) | Length | 117 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | - |
| Locus tag | AW79_RS25180 | Protein ID | WP_000124640.1 |
| Coordinates | 67146..67448 (+) | Length | 101 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| AW79_RS25120 | 61860..62039 | - | 180 | Protein_64 | helix-turn-helix transcriptional regulator | - |
| AW79_RS25125 | 62346..63050 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| AW79_RS25135 | 63265..63762 | - | 498 | WP_000062185.1 | hypothetical protein | - |
| AW79_RS25140 | 63765..64253 | - | 489 | WP_001273096.1 | DUF1643 domain-containing protein | - |
| AW79_RS25145 | 64350..64685 | + | 336 | WP_000683476.1 | hypothetical protein | - |
| AW79_RS25150 | 64700..65170 | - | 471 | WP_001281821.1 | hypothetical protein | - |
| AW79_RS25155 | 65163..65534 | - | 372 | WP_000516916.1 | hypothetical protein | - |
| AW79_RS25160 | 65545..65739 | - | 195 | WP_000343597.1 | hypothetical protein | - |
| AW79_RS25170 | 66080..66628 | - | 549 | WP_001061574.1 | transcriptional regulator | - |
| AW79_RS25175 | 66791..67141 | + | 351 | WP_000270043.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| AW79_RS25180 | 67146..67448 | + | 303 | WP_000124640.1 | XRE family transcriptional regulator | Antitoxin |
| AW79_RS25185 | 67475..67768 | - | 294 | WP_001239997.1 | chromosome segregation protein ParM | - |
| AW79_RS25190 | 67856..68128 | - | 273 | WP_001043047.1 | HU family DNA-binding protein | - |
| AW79_RS25195 | 68186..68713 | - | 528 | WP_001236377.1 | thermonuclease family protein | - |
| AW79_RS25205 | 68944..69801 | - | 858 | WP_001167032.1 | hypothetical protein | - |
| AW79_RS25210 | 69788..70018 | - | 231 | WP_000972663.1 | hypothetical protein | - |
| AW79_RS25215 | 70018..70536 | - | 519 | WP_000210756.1 | nitrite reductase | - |
| AW79_RS25220 | 70533..70979 | - | 447 | WP_000919345.1 | Fe3+-siderophore ABC transporter permease | - |
| AW79_RS25225 | 70979..71338 | - | 360 | WP_000422768.1 | hypothetical protein | - |
| AW79_RS25230 | 71395..71823 | - | 429 | WP_000591074.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..125113 | 125113 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 15014.38 Da Isoelectric Point: 12.8644
>T90027 WP_000270043.1 NZ_CP025275:66791-67141 [Salmonella enterica subsp. enterica serovar Newport str.]
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Download Length: 351 bp
>T90027 NZ_CP025275:66791-67141 [Salmonella enterica subsp. enterica serovar Newport str.]
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Antitoxin
Download Length: 101 a.a. Molecular weight: 12963.60 Da Isoelectric Point: 12.8000
>AT90027 WP_000124640.1 NZ_CP025275:67146-67448 [Salmonella enterica subsp. enterica serovar Newport str.]
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Download Length: 303 bp
>AT90027 NZ_CP025275:67146-67448 [Salmonella enterica subsp. enterica serovar Newport str.]
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Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|