Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 3700668..3700890 Replicon chromosome
Accession NZ_CP025268
Organism Escherichia coli str. K-12 substr. MG1655 strain K-12

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag CXP41_RS19295 Protein ID WP_000141634.1
Coordinates 3700668..3700775 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 3700824..3700890 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CXP41_RS19270 3695921..3696673 - 753 Protein_3530 cellulose biosynthesis protein BcsQ -
CXP41_RS19275 3696685..3696873 - 189 WP_001063318.1 YhjR family protein -
CXP41_RS19280 3697146..3698717 + 1572 WP_001204931.1 cellulose biosynthesis protein BcsE -
CXP41_RS19285 3698714..3698905 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
CXP41_RS19290 3698902..3700581 + 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
CXP41_RS19295 3700668..3700775 - 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
- 3700824..3700890 + 67 - - Antitoxin
CXP41_RS19310 3701251..3702522 + 1272 WP_001295225.1 transporter -
CXP41_RS19315 3702552..3703556 - 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
CXP41_RS19320 3703553..3704536 - 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
CXP41_RS19325 3704547..3705449 - 903 WP_000084677.1 dipeptide ABC transporter permease DppC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T90014 WP_000141634.1 NZ_CP025268:c3700775-3700668 [Escherichia coli str. K-12 substr. MG1655]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T90014 NZ_CP025268:c3700775-3700668 [Escherichia coli str. K-12 substr. MG1655]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 67 bp

>AT90014 NZ_CP025268:3700824-3700890 [Escherichia coli str. K-12 substr. MG1655]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References