Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 24101..24359 Replicon chromosome
Accession NZ_CP025251
Organism Escherichia coli strain BH100 substr. MG2017

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag BH100B_RS00140 Protein ID WP_000809168.1
Coordinates 24101..24253 (-) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 24302..24359 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BH100B_RS00120 19346..20059 - 714 WP_001102393.1 acidic protein MsyB -
BH100B_RS00125 20085..20489 - 405 WP_000843689.1 DUF2541 family protein -
BH100B_RS00130 20861..22777 + 1917 WP_000516135.1 molecular chaperone DnaK -
BH100B_RS00135 22866..23996 + 1131 WP_001118464.1 molecular chaperone DnaJ -
BH100B_RS00140 24101..24253 - 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
- 24302..24359 + 58 - - Antitoxin
BH100B_RS00150 24868..25629 + 762 WP_099989640.1 hypothetical protein -
BH100B_RS00155 25649..27142 + 1494 WP_001314416.1 sulfatase-like hydrolase/transferase -
BH100B_RS00160 27271..28530 + 1260 WP_000494927.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T89929 WP_000809168.1 NZ_CP025251:c24253-24101 [Escherichia coli]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

>T89929 NZ_CP025251:c24253-24101 [Escherichia coli]
ATGAAGCAGCATAAGGCGATGATTGTCGCCCTGATCGTCATCTGTATCACCGCCGTAGTGGCGGCGCTGGTAACGAGAAA
AGACCTCTGTGAGGTTCACATCCGAACTGGCCAGACGGAGGTTGCTGTTTTCACGGCTTACGAATCCGAGTAA

Antitoxin


Download         Length: 58 bp

>AT89929 NZ_CP025251:24302-24359 [Escherichia coli]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References