Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/COG4683-HTH_37 |
| Location | 14452..15109 | Replicon | plasmid pSNE1-1929 |
| Accession | NZ_CP025242 | ||
| Organism | Salmonella enterica subsp. enterica serovar Newport str. USDA-ARS-USMARC-1929 | ||
Toxin (Protein)
| Gene name | higB | Uniprot ID | U3PDC3 |
| Locus tag | AW85_RS24580 | Protein ID | WP_000270043.1 |
| Coordinates | 14759..15109 (-) | Length | 117 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | - |
| Locus tag | AW85_RS24575 | Protein ID | WP_000124640.1 |
| Coordinates | 14452..14754 (-) | Length | 101 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| AW85_RS24525 | 10077..10505 | + | 429 | WP_000591074.1 | hypothetical protein | - |
| AW85_RS24530 | 10562..10921 | + | 360 | WP_000422768.1 | hypothetical protein | - |
| AW85_RS24535 | 10921..11367 | + | 447 | WP_000919345.1 | Fe3+-siderophore ABC transporter permease | - |
| AW85_RS24540 | 11364..11882 | + | 519 | WP_000210756.1 | nitrite reductase | - |
| AW85_RS24545 | 11882..12112 | + | 231 | WP_000972663.1 | hypothetical protein | - |
| AW85_RS24550 | 12099..12956 | + | 858 | WP_001167032.1 | hypothetical protein | - |
| AW85_RS24560 | 13187..13714 | + | 528 | WP_001236377.1 | thermonuclease family protein | - |
| AW85_RS24565 | 13772..14044 | + | 273 | WP_001043047.1 | HU family DNA-binding protein | - |
| AW85_RS24570 | 14132..14425 | + | 294 | WP_001239997.1 | chromosome segregation protein ParM | - |
| AW85_RS24575 | 14452..14754 | - | 303 | WP_000124640.1 | XRE family transcriptional regulator | Antitoxin |
| AW85_RS24580 | 14759..15109 | - | 351 | WP_000270043.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| AW85_RS24585 | 15272..15820 | + | 549 | WP_001061574.1 | transcriptional regulator | - |
| AW85_RS24595 | 16161..16355 | + | 195 | WP_000343597.1 | hypothetical protein | - |
| AW85_RS24600 | 16366..16737 | + | 372 | WP_000516916.1 | hypothetical protein | - |
| AW85_RS24605 | 16730..17200 | + | 471 | WP_001281821.1 | hypothetical protein | - |
| AW85_RS24610 | 17215..17550 | - | 336 | WP_000683476.1 | hypothetical protein | - |
| AW85_RS24615 | 17647..18135 | + | 489 | WP_001273096.1 | DUF1643 domain-containing protein | - |
| AW85_RS24620 | 18138..18635 | + | 498 | WP_000062185.1 | hypothetical protein | - |
| AW85_RS24630 | 18850..19554 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| AW85_RS24635 | 19619..19798 | - | 180 | Protein_32 | helix-turn-helix transcriptional regulator | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..98400 | 98400 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 17237.68 Da Isoelectric Point: 5.5500
>T89925 WP_000270043.1 NZ_CP025242:c15109-14759 [Salmonella enterica subsp. enterica serovar Newport str.]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
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FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
Download Length: 351 bp
>T89925 NZ_CP025242:c15109-14759 [Salmonella enterica subsp. enterica serovar Newport str.]
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Antitoxin
Download Length: 101 a.a. Molecular weight: 14882.85 Da Isoelectric Point: 5.5500
>AT89925 WP_000124640.1 NZ_CP025242:c14754-14452 [Salmonella enterica subsp. enterica serovar Newport str.]
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Download Length: 303 bp
>AT89925 NZ_CP025242:c14754-14452 [Salmonella enterica subsp. enterica serovar Newport str.]
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Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|