Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 2622842..2623348 Replicon chromosome
Accession NZ_CP025198
Organism Acidipropionibacterium virtanenii strain JS278

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag JS278_RS12200 Protein ID WP_114045428.1
Coordinates 2622842..2623096 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag JS278_RS12205 Protein ID WP_114046308.1
Coordinates 2623097..2623348 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JS278_RS12175 2619332..2619613 - 282 WP_114045423.1 DUF3263 domain-containing protein -
JS278_RS12180 2619754..2620935 + 1182 WP_114045424.1 mannose-6-phosphate isomerase, class I -
JS278_RS12185 2620974..2621438 + 465 WP_114045425.1 S-ribosylhomocysteine lyase -
JS278_RS12190 2621485..2622117 - 633 WP_181833714.1 RES family NAD+ phosphorylase -
JS278_RS12195 2622114..2622458 - 345 WP_114045427.1 hypothetical protein -
JS278_RS16050 2622539..2622700 - 162 WP_181833715.1 hypothetical protein -
JS278_RS12200 2622842..2623096 - 255 WP_114045428.1 Txe/YoeB family addiction module toxin Toxin
JS278_RS12205 2623097..2623348 - 252 WP_114046308.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
JS278_RS16055 2623658..2623804 - 147 WP_181833716.1 hypothetical protein -
JS278_RS12215 2624078..2624767 + 690 Protein_2378 transposase family protein -
JS278_RS12225 2625036..2625806 - 771 WP_114046310.1 cobalamin-binding protein -
JS278_RS12230 2625806..2626759 - 954 WP_114046309.1 adenosylcobinamide-GDP ribazoletransferase -
JS278_RS12235 2626756..2627322 - 567 WP_114045430.1 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-69)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9915.23 Da        Isoelectric Point: 7.9799

>T89864 WP_114045428.1 NZ_CP025198:c2623096-2622842 [Acidipropionibacterium virtanenii]
VRLVWDRNAWADYTYWQTADRRVLKRINTLIDACLRDPFAGIGKPEQLKYGAPGSWSRRITDEDRLVYLADGEDLVILQA
RYHY

Download         Length: 255 bp

>T89864 NZ_CP025198:c2623096-2622842 [Acidipropionibacterium virtanenii]
GTGCGGCTGGTCTGGGACCGCAACGCCTGGGCGGACTACACCTACTGGCAGACCGCGGACCGCAGAGTCCTCAAGCGCAT
CAACACGCTGATCGACGCCTGCCTTCGGGACCCGTTCGCCGGCATCGGCAAGCCTGAGCAGCTCAAATACGGTGCCCCTG
GGTCGTGGTCCCGGCGGATCACCGACGAGGACCGGCTGGTGTACCTGGCCGACGGTGAGGATCTCGTCATCCTCCAAGCC
CGCTATCACTACTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9452.43 Da        Isoelectric Point: 4.8307

>AT89864 WP_114046308.1 NZ_CP025198:c2623348-2623097 [Acidipropionibacterium virtanenii]
MSLSASEARRTLFPLIERVNQDRDAVEIVSKHGNAVLMPADEYTAWQETAYLFRSPANARRLLDAYERARSGGTETHDLD
RED

Download         Length: 252 bp

>AT89864 NZ_CP025198:c2623348-2623097 [Acidipropionibacterium virtanenii]
ATGTCCCTGTCGGCCTCTGAGGCGCGTAGGACCCTGTTCCCTCTCATTGAGCGGGTCAACCAGGACCGCGACGCCGTCGA
GATCGTCTCGAAGCACGGCAACGCCGTCCTCATGCCGGCCGACGAGTACACGGCCTGGCAGGAGACCGCCTATCTGTTCC
GTTCCCCGGCCAACGCCCGCCGGCTGCTCGACGCCTACGAGCGCGCTCGATCCGGCGGGACCGAGACTCACGATCTGGAC
CGGGAGGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References