Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 711944..712450 Replicon chromosome
Accession NZ_CP025198
Organism Acidipropionibacterium virtanenii strain JS278

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag JS278_RS03130 Protein ID WP_114043924.1
Coordinates 711944..712198 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag JS278_RS03135 Protein ID WP_114043925.1
Coordinates 712199..712450 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JS278_RS03110 707336..708964 + 1629 WP_114046082.1 alpha/beta hydrolase -
JS278_RS03115 709199..709528 + 330 WP_114043922.1 hypothetical protein -
JS278_RS03120 709756..711474 - 1719 WP_114043923.1 DUF885 domain-containing protein -
JS278_RS03130 711944..712198 - 255 WP_114043924.1 Txe/YoeB family addiction module toxin Toxin
JS278_RS03135 712199..712450 - 252 WP_114043925.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
JS278_RS03140 712603..713232 - 630 WP_114043926.1 CGNR zinc finger domain-containing protein -
JS278_RS03145 713516..713956 + 441 WP_114043927.1 hypothetical protein -
JS278_RS03150 714005..714538 - 534 WP_114043928.1 hypothetical protein -
JS278_RS03155 714693..716039 + 1347 WP_114043929.1 FAD-dependent oxidoreductase -
JS278_RS03160 716165..716725 - 561 WP_114043930.1 NAD(P)H-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(3-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-69)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9986.31 Da        Isoelectric Point: 7.2748

>T89858 WP_114043924.1 NZ_CP025198:c712198-711944 [Acidipropionibacterium virtanenii]
VRLVWDRDAWADYTHWQTADRRILKRINTLIDACLRDPFEGIGKPEQLKYGASGAWSRRITDEHRLVYLVDGDDLIILQA
RYHY

Download         Length: 255 bp

>T89858 NZ_CP025198:c712198-711944 [Acidipropionibacterium virtanenii]
GTGCGCCTCGTCTGGGATCGCGACGCCTGGGCCGACTACACGCACTGGCAGACGGCGGACCGCCGCATCCTCAAGCGAAT
CAACACGCTCATCGACGCCTGCCTGCGTGACCCGTTCGAAGGTATCGGCAAACCCGAGCAGCTCAAGTACGGCGCCTCTG
GAGCGTGGTCCAGACGGATCACCGACGAGCACCGGCTTGTCTACCTCGTTGACGGCGATGACCTGATCATCCTCCAGGCC
CGCTACCACTACTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9379.42 Da        Isoelectric Point: 4.8668

>AT89858 WP_114043925.1 NZ_CP025198:c712450-712199 [Acidipropionibacterium virtanenii]
MSLSASEARRTLFPLIEKVNEDREAVEIVSKHGNAVLMPAEEYAAWQETAYLFRSPANARRLLDAYERARSGATEAHDLD
RES

Download         Length: 252 bp

>AT89858 NZ_CP025198:c712450-712199 [Acidipropionibacterium virtanenii]
ATGTCTCTGAGCGCCAGTGAGGCACGACGGACACTGTTCCCTCTCATAGAGAAGGTCAACGAGGATCGCGAGGCCGTCGA
GATCGTCTCCAAGCACGGCAACGCGGTGCTCATGCCCGCCGAGGAGTACGCGGCCTGGCAGGAGACCGCGTACCTGTTCC
GGTCGCCGGCAAATGCTCGACGCCTGTTGGATGCGTACGAGCGCGCCCGGTCCGGAGCCACCGAGGCTCACGACCTGGAC
CGGGAGAGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References