Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2421271..2421455 Replicon chromosome
Accession NZ_CP025023
Organism Staphylococcus argenteus strain XNO106

Toxin (Protein)


Gene name SprA2 Uniprot ID -
Locus tag CKO49_RS11955 Protein ID WP_000482653.1
Coordinates 2421348..2421455 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2421271..2421331 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CKO49_RS11940 2417123..2418856 - 1734 WP_031787186.1 ABC transporter ATP-binding protein/permease -
CKO49_RS11945 2418881..2420644 - 1764 WP_031787187.1 ABC transporter ATP-binding protein/permease -
- 2421271..2421331 + 61 - - Antitoxin
CKO49_RS11955 2421348..2421455 - 108 WP_000482653.1 type I toxin-antitoxin system Fst family toxin Toxin
CKO49_RS11960 2421589..2421975 - 387 WP_000779346.1 flippase GtxA -
CKO49_RS11965 2422243..2423385 + 1143 WP_100848602.1 glycerate kinase -
CKO49_RS11970 2423444..2424103 + 660 WP_000831306.1 membrane protein -
CKO49_RS11975 2424288..2425499 + 1212 WP_031787189.1 multidrug effflux MFS transporter -
CKO49_RS11980 2425615..2426094 - 480 WP_031787190.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sbi / hlgA / hlgA / hlgC / hlgB 2405910..2421975 16065


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4025.81 Da        Isoelectric Point: 11.0582

>T89527 WP_000482653.1 NZ_CP025023:c2421455-2421348 [Staphylococcus argenteus]
MFNLLINIMTTAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T89527 NZ_CP025023:c2421455-2421348 [Staphylococcus argenteus]
ATGTTCAATTTATTGATTAACATCATGACTACAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT89527 NZ_CP025023:2421271-2421331 [Staphylococcus argenteus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References