Detailed information of TA system TA089519

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprG2-SprA2AS/-
• Location: 1007856..1008073
• Replicon: chromosome
• Accession: NZ_CP025023
• Organism: Staphylococcus argenteus strain XNO106

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: CKO49_RS04960
• Protein ID: WP_031787354.1
• Coordinates: 1007856..1007963 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	1007958..1008073 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CKO49_RS04935	1004535..1005104	-	570	WP_000287261.1	competence protein ComK	-
CKO49_RS04940	1005314..1005532	+	219	WP_000876831.1	IDEAL domain-containing protein	-
CKO49_RS04945	1005613..1006599	-	987	WP_000668810.1	lipoate--protein ligase	-
CKO49_RS04950	1006794..1006970	+	177	WP_000214898.1	YkvS family protein	-
CKO49_RS04955	1006985..1007587	+	603	WP_031787353.1	CPBP family intramembrane metalloprotease	-
CKO49_RS04960	1007856..1007963	+	108	WP_031787354.1	putative holin-like toxin	Toxin
-	1007958..1008073	-	116	-	-	Antitoxin
CKO49_RS04965	1008598..1008879	+	282	Protein_946	lactococcin 972 family bacteriocin	-
CKO49_RS04970	1008923..1010887	+	1965	WP_031787355.1	bacteriocin-associated integral membrane family protein	-
CKO49_RS04975	1010890..1011210	+	321	WP_031787356.1	YxeA family protein	-
CKO49_RS04980	1011207..1011848	+	642	WP_031787357.1	ABC transporter ATP-binding protein	-
CKO49_RS04985	1011936..1012196	-	261	WP_169929182.1	hypothetical protein	-
CKO49_RS04990	1012511..1012798	+	288	WP_000410715.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3815.72 Da
• Isoelectric Point: 10.8004

>T89519 WP_031787354.1 NZ_CP025023:1007856-1007963 [Staphylococcus argenteus]
VISIANALHLMLSFGMFIVTFIGIVVAIININNKK

Nucleotide

• Length: 108 bp

>T89519 NZ_CP025023:1007856-1007963 [Staphylococcus argenteus]
GTGATATCTATTGCAAACGCATTACATTTAATGTTAAGTTTCGGTATGTTTATCGTAACTTTCATTGGTATAGTAGTCGC
AATAATTAATATAAACAATAAAAAATAA

Antitoxin

Nucleotide

• Length: 116 bp

>AT89519 NZ_CP025023:c1008073-1007958 [Staphylococcus argenteus]
GTAAAAAGACGACATGCAGGAACATGTCGCCTATTGAGCCCGTTAAAAAGACGGTGACTAAATGAGATTTTCTTTAACCA
TCATTCGTTGTCAAAGTTTTGAAATGATGGTTATTT

Structures

Antitoxin