Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafN-yafO (relBE)/YafO-YafN
Location 1255857..1256545 Replicon chromosome
Accession NZ_CP025000
Organism Idiomarina sp. X4

Toxin (Protein)


Gene name yafO Uniprot ID -
Locus tag CWC33_RS06005 Protein ID WP_100691199.1
Coordinates 1256147..1256545 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name yafN Uniprot ID -
Locus tag CWC33_RS06000 Protein ID WP_100691198.1
Coordinates 1255857..1256150 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CWC33_RS05975 1251146..1251997 + 852 WP_100691193.1 hypothetical protein -
CWC33_RS05980 1251992..1253095 - 1104 WP_100691194.1 DNA cytosine methyltransferase -
CWC33_RS05985 1253096..1254853 - 1758 WP_100691195.1 Eco57I restriction-modification methylase domain-containing protein -
CWC33_RS05995 1255362..1255685 - 324 WP_100691197.1 HigA family addiction module antidote protein -
CWC33_RS06000 1255857..1256150 + 294 WP_100691198.1 type I toxin-antitoxin system antitoxin YafN Antitoxin
CWC33_RS06005 1256147..1256545 + 399 WP_100691199.1 type II toxin-antitoxin system YafO family toxin Toxin
CWC33_RS06010 1256542..1257207 - 666 WP_100691200.1 hypothetical protein -
CWC33_RS06020 1257716..1258204 + 489 WP_053953442.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin YafO

(27-130)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 15400.59 Da        Isoelectric Point: 7.0383

>T89445 WP_100691199.1 NZ_CP025000:1256147-1256545 [Idiomarina sp. X4]
VIRVFKSKQIRQQLTDTELDALVRDFKRYKSGEGVPDFFGRDERYDHPDTFPVLRDNEVMHLHLENPDEPWPLHCIQFSK
KSNTHLVYCPAAMTSNCYLLMVILDPSAHNKAWSSSVMLPLGTMAENFRNKY

Download         Length: 399 bp

>T89445 NZ_CP025000:1256147-1256545 [Idiomarina sp. X4]
GTGATTAGGGTTTTTAAGAGCAAACAGATTCGTCAGCAATTAACAGATACGGAACTGGATGCATTAGTTAGAGACTTTAA
ACGTTATAAAAGTGGTGAAGGCGTGCCCGACTTTTTCGGGCGCGATGAACGTTACGATCACCCCGACACTTTTCCCGTTC
TTCGTGACAATGAAGTAATGCACTTGCATCTGGAAAACCCCGATGAGCCATGGCCTTTGCATTGCATTCAATTTTCTAAG
AAAAGTAATACCCACTTGGTTTATTGCCCTGCTGCTATGACTTCTAACTGTTACTTACTCATGGTGATTTTAGACCCGTC
AGCACACAATAAAGCCTGGAGTAGTTCGGTTATGCTGCCTTTAGGAACAATGGCAGAGAACTTCAGAAATAAGTACTAA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10743.21 Da        Isoelectric Point: 4.8892

>AT89445 WP_100691198.1 NZ_CP025000:1255857-1256150 [Idiomarina sp. X4]
MNTQTILAEKTVSASDVRKHPCQYFEAEPVAVLSHNKTAGYMVGAELFEAMVRQLEACNPKVESLFRPTAARLKAISADA
ERLLAEAKKSDLDDFEE

Download         Length: 294 bp

>AT89445 NZ_CP025000:1255857-1256150 [Idiomarina sp. X4]
ATGAACACACAAACAATATTGGCTGAAAAAACAGTATCTGCCAGCGATGTACGCAAGCATCCCTGCCAGTATTTTGAAGC
TGAACCTGTGGCGGTACTCTCCCACAATAAAACCGCTGGCTATATGGTGGGTGCCGAATTATTTGAAGCTATGGTGCGCC
AGTTGGAAGCCTGTAACCCTAAAGTAGAATCCCTTTTTAGGCCGACAGCAGCGCGCCTAAAGGCTATTAGCGCCGACGCA
GAGAGGCTTTTAGCTGAAGCGAAAAAGTCTGACCTGGATGACTTTGAAGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References