Detailed information of TA system TA089431

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1336192..1336372
• Replicon: chromosome
• Accession: NZ_CP024998
• Organism: Staphylococcus aureus strain 55-99-44

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: CU118_RS14195
• Protein ID: WP_001801861.1
• Coordinates: 1336192..1336287 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1336315..1336372 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CU118_RS06590	1331593..1332219	+	627	WP_054190584.1	hypothetical protein	-
CU118_RS06595	1332260..1332601	+	342	WP_054190585.1	DUF3969 family protein	-
CU118_RS06600	1332702..1333274	+	573	WP_054190586.1	hypothetical protein	-
CU118_RS06605	1333651..1334487	+	837	WP_054190587.1	ABC transporter ATP-binding protein	-
CU118_RS06615	1335294..1335740	-	447	WP_054190589.1	DUF1433 domain-containing protein	-
CU118_RS14195	1336192..1336287	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1336315..1336372	-	58	-	-	Antitoxin
CU118_RS06625	1336410..1336511	+	102	WP_054190590.1	hypothetical protein	-
CU118_RS06630	1336497..1336764	-	268	Protein_1268	transposase	-
CU118_RS14250	1336796..1337158	+	363	WP_054190591.1	hypothetical protein	-
CU118_RS06640	1337180..1337683	+	504	WP_054190592.1	hypothetical protein	-
CU118_RS06650	1338238..1338681	-	444	WP_054190593.1	DUF1433 domain-containing protein	-
CU118_RS06655	1338681..1339124	-	444	WP_054190594.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T89431 WP_001801861.1 NZ_CP024998:1336192-1336287 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T89431 NZ_CP024998:1336192-1336287 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT89431 NZ_CP024998:c1336372-1336315 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin