Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1336192..1336372 Replicon chromosome
Accession NZ_CP024998
Organism Staphylococcus aureus strain 55-99-44

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag CU118_RS14195 Protein ID WP_001801861.1
Coordinates 1336192..1336287 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1336315..1336372 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CU118_RS06590 1331593..1332219 + 627 WP_054190584.1 hypothetical protein -
CU118_RS06595 1332260..1332601 + 342 WP_054190585.1 DUF3969 family protein -
CU118_RS06600 1332702..1333274 + 573 WP_054190586.1 hypothetical protein -
CU118_RS06605 1333651..1334487 + 837 WP_054190587.1 ABC transporter ATP-binding protein -
CU118_RS06615 1335294..1335740 - 447 WP_054190589.1 DUF1433 domain-containing protein -
CU118_RS14195 1336192..1336287 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1336315..1336372 - 58 - - Antitoxin
CU118_RS06625 1336410..1336511 + 102 WP_054190590.1 hypothetical protein -
CU118_RS06630 1336497..1336764 - 268 Protein_1268 transposase -
CU118_RS14250 1336796..1337158 + 363 WP_054190591.1 hypothetical protein -
CU118_RS06640 1337180..1337683 + 504 WP_054190592.1 hypothetical protein -
CU118_RS06650 1338238..1338681 - 444 WP_054190593.1 DUF1433 domain-containing protein -
CU118_RS06655 1338681..1339124 - 444 WP_054190594.1 DUF1433 domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T89431 WP_001801861.1 NZ_CP024998:1336192-1336287 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T89431 NZ_CP024998:1336192-1336287 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT89431 NZ_CP024998:c1336372-1336315 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References