Detailed information of TA system TA089426

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 448500..448749
• Replicon: chromosome
• Accession: NZ_CP024998
• Organism: Staphylococcus aureus strain 55-99-44

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: CU118_RS14185
• Protein ID: WP_000623369.1
• Coordinates: 448500..448607 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF2
Locus tag	-
Coordinates	448602..448749 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CU118_RS02210	445166..445735	-	570	WP_000287265.1	competence protein ComK	-
CU118_RS02215	445945..446163	+	219	WP_000876826.1	IDEAL domain-containing protein	-
CU118_RS02220	446252..447238	-	987	WP_054190346.1	lipoate--protein ligase	-
CU118_RS02225	447437..447613	+	177	WP_000214898.1	YkvS family protein	-
CU118_RS02230	447628..448230	+	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
CU118_RS14185	448500..448607	+	108	WP_000623369.1	putative holin-like toxin	Toxin
-	448602..448749	-	148	-	-	Antitoxin
CU118_RS02235	449245..449529	+	285	WP_054190345.1	lactococcin 972 family bacteriocin	-
CU118_RS02240	449573..451537	+	1965	WP_054190344.1	bacteriocin-associated integral membrane family protein	-
CU118_RS02245	451540..451860	+	321	WP_054190343.1	YxeA family protein	-
CU118_RS02250	451857..452498	+	642	WP_054190342.1	ABC transporter ATP-binding protein	-
CU118_RS02255	452586..452876	-	291	WP_077446589.1	hypothetical protein	-
CU118_RS02260	453017..453154	+	138	WP_077446590.1	poly(glycerol-phosphate) alpha-glucosyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T89426 WP_000623369.1 NZ_CP024998:448500-448607 [Staphylococcus aureus]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

>T89426 NZ_CP024998:448500-448607 [Staphylococcus aureus]
GTGATATCTATTGCAAATGCATTACATTTAATGTTAAGTTTCGGTATGTTTATTGTCACTTTCATTGGTGTAGTAGTCGC
AATAATTAATTTAAACAATAAAAAATAA

Antitoxin

Nucleotide

• Length: 148 bp

>AT89426 NZ_CP024998:c448749-448602 [Staphylococcus aureus]
CAATTAAATAAAAGATATGTTACTATAATAATGTAAAAAGACGACATGCAGGAACATGTCGCCTATTGAGCCCGTTAAAA
AGACGGTGACTAAATGAGATTTTCTTTAACCATCATTCGTTGTCAAAGTTTGGAAATGATGGTTATTT

Structures

Antitoxin