89355

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 581073..581331 Replicon chromosome
Accession NZ_CP024970
Organism Erwinia amylovora strain E-2

Toxin (Protein)


Gene name hok Uniprot ID D4I1C1
Locus tag AD997_RS02655 Protein ID WP_004160031.1
Coordinates 581173..581331 (+) Length 53 a.a.

Antitoxin (RNA)


Gene name sok
Locus tag -
Coordinates 581073..581119 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AD997_RS18250 576519..576662 - 144 WP_004160049.1 hypothetical protein -
AD997_RS02610 577135..577527 - 393 WP_004160048.1 DoxX family protein -
AD997_RS02615 577737..578018 - 282 WP_004160039.1 YqjK-like family protein -
AD997_RS02620 578018..578410 - 393 WP_004160038.1 phage holin family protein -
AD997_RS02625 578412..578717 - 306 WP_004160037.1 DUF883 family protein -
AD997_RS02630 578760..579131 - 372 WP_004160036.1 DUF1090 domain-containing protein -
AD997_RS02635 579299..579691 - 393 WP_004160035.1 EnvZ/OmpR regulon moderator MzrA -
AD997_RS02640 579688..580362 - 675 WP_004160034.1 DedA family protein -
- 581073..581119 - 47 - - Antitoxin
AD997_RS02655 581173..581331 + 159 WP_004160031.1 type I toxin-antitoxin system Hok family toxin Toxin
AD997_RS02660 581475..582707 - 1233 WP_004160030.1 serine/threonine transporter SstT -
AD997_RS02665 582942..583922 - 981 WP_013035818.1 TerC family protein -
AD997_RS02670 584335..586011 + 1677 WP_100618455.1 chloride channel protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(8-48)


Sequences

Toxin        


Download         Length: 53 a.a.        Molecular weight: 6038.32 Da        Isoelectric Point: 8.4901

>T89355 WP_004160031.1 NZ_CP024970:581173-581331 [Erwinia amylovora]
MKLPANCLIWCVLIVCVTLLIFTYLTRKSLCEIRYKDGYREVAAFMAYESGK

Download         Length: 159 bp

>T89355 NZ_CP024970:581173-581331 [Erwinia amylovora]
ATGAAACTGCCAGCGAACTGTCTTATCTGGTGCGTACTTATAGTGTGTGTCACGCTTTTAATATTCACATATCTGACACG
AAAATCGCTCTGCGAAATTCGCTATAAGGATGGTTACAGGGAGGTGGCCGCTTTCATGGCTTACGAATCCGGCAAGTAG

Antitoxin


Download         Length: 47 bp

>AT89355 NZ_CP024970:c581119-581073 [Erwinia amylovora]
GCATGCAGATGGCCTCGTGGATTAATGAAAATTAACTACGGGGCTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A831A7I1

Antitoxin

Download structure file

References