89341

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 82448..83799 Replicon chromosome
Accession NZ_CP024956
Organism Pectobacterium atrosepticum strain 36A

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag CVS35_RS00365 Protein ID WP_039296545.1
Coordinates 82448..83488 (-) Length 347 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag CVS35_RS00370 Protein ID WP_039296542.1
Coordinates 83485..83799 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CVS35_RS00335 77602..78954 + 1353 WP_039296560.1 glutathione-disulfide reductase -
CVS35_RS00340 79057..79344 - 288 WP_011091708.1 type II toxin-antitoxin system RelE/ParE family toxin -
CVS35_RS00345 79341..79592 - 252 WP_010281712.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
CVS35_RS00350 79848..80753 + 906 WP_039296557.1 siderophore-interacting protein -
CVS35_RS00355 80788..81543 - 756 WP_039296553.1 thiol:disulfide interchange protein DsbG -
CVS35_RS00360 81764..82387 + 624 WP_039296550.1 LysE family translocator -
CVS35_RS00365 82448..83488 - 1041 WP_039296545.1 HipA domain-containing protein Toxin
CVS35_RS00370 83485..83799 - 315 WP_039296542.1 HipA N-terminal domain-containing protein Antitoxin
CVS35_RS00375 83784..84110 - 327 WP_039296540.1 helix-turn-helix domain-containing protein -
CVS35_RS00380 84272..85144 - 873 WP_039296537.1 LysR family transcriptional regulator -
CVS35_RS00385 85247..85756 + 510 WP_011091713.1 phenolic acid decarboxylase -
CVS35_RS00390 85993..86430 - 438 WP_039296533.1 RICIN domain-containing protein -
CVS35_RS00395 86837..87973 - 1137 WP_039296529.1 alkylhydroperoxidase domain protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(57-307)

Antitoxin

HipA, N-terminal subdomain 1

(5-98)


Sequences

Toxin        


Download         Length: 347 a.a.        Molecular weight: 39575.52 Da        Isoelectric Point: 6.5563

>T89341 WP_039296545.1 NZ_CP024956:c83488-82448 [Pectobacterium atrosepticum]
MTRCRILLTPLAHEEEIATGYSRKGLKHLAGSIHASPTLRFTRQQFMHDLPQTQKGMSISGYQPKIQMVLEDRTFTVVDH
QGLYILKPSPIEFPHLAENEHATMTLMARLGFAVPPHGLLRFKPEQMDDESEFAFVIKRFDRDEKTGHPIHQEQLDGAMG
IGEKFGKIRADGRQYVSYERLALFLSEHVNDNIVFKIDLFRRIAYTYMLGNNDMHLRNFGLIHSRSGQLMLAPIYDFVSV
APYPAYFSSCFMALPLLIQEEGDEALAPGFETAYGEYLGMDFMLFGQHIGLSENLTRKLLADLIKEAEYVESTYRDSFMP
ANAIDATLRCYRHRLNLMSVLDAKQI

Download         Length: 1041 bp

>T89341 NZ_CP024956:c83488-82448 [Pectobacterium atrosepticum]
ATGACAAGATGTCGAATTTTGCTGACACCGCTGGCACATGAAGAAGAAATTGCCACAGGCTATAGCCGTAAAGGGTTGAA
GCATCTGGCAGGATCAATACACGCTTCCCCGACCTTACGTTTCACCCGCCAGCAATTCATGCACGACCTGCCACAAACGC
AGAAAGGCATGAGTATTTCTGGTTATCAGCCCAAAATTCAGATGGTATTAGAAGATCGAACGTTTACCGTCGTTGATCAT
CAAGGGCTATATATTCTCAAACCCTCACCGATTGAATTTCCCCATTTGGCAGAAAACGAACATGCCACAATGACGCTAAT
GGCGCGTCTGGGATTTGCCGTCCCACCACACGGATTACTTCGTTTTAAACCGGAACAGATGGATGACGAATCTGAGTTTG
CTTTCGTTATTAAGCGCTTCGATCGCGACGAAAAAACAGGCCACCCTATCCATCAGGAACAGTTGGACGGTGCGATGGGG
ATCGGTGAAAAATTCGGTAAAATACGTGCAGATGGCAGACAATATGTCAGCTACGAGAGGTTGGCGTTATTCCTTAGCGA
ACACGTTAATGACAATATTGTCTTCAAAATAGATCTGTTCCGCCGCATCGCTTACACCTACATGCTGGGTAACAACGACA
TGCATCTGCGTAATTTTGGCCTGATACATTCGCGTTCAGGCCAGTTAATGCTGGCTCCTATTTATGATTTTGTTTCCGTC
GCCCCTTATCCCGCCTATTTTTCTTCCTGCTTCATGGCATTACCGCTGTTGATTCAAGAAGAAGGTGACGAGGCACTCGC
ACCAGGGTTTGAAACTGCATATGGCGAATACCTTGGTATGGATTTCATGCTGTTCGGTCAGCATATTGGGTTGAGTGAAA
ACCTCACTAGGAAGTTGCTGGCAGACCTCATCAAAGAAGCTGAATACGTTGAATCAACCTATCGGGATTCCTTTATGCCT
GCGAACGCTATTGATGCAACGCTGCGGTGCTATCGACACCGCCTGAATCTTATGAGCGTTCTCGATGCAAAGCAGATTTA
G

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11869.67 Da        Isoelectric Point: 9.2317

>AT89341 WP_039296542.1 NZ_CP024956:c83799-83485 [Pectobacterium atrosepticum]
VRRQVKVYLYGVHIGQLSQDDEGYLFEYKKSYLGPPLSLSLPLQTGIFRSKSLLPYFASLAPEGWLRRQYSQLQHLDEKD
LFGILIQNGKNLIGAVQLIAEDKS

Download         Length: 315 bp

>AT89341 NZ_CP024956:c83799-83485 [Pectobacterium atrosepticum]
GTGCGCCGTCAGGTAAAGGTCTATCTTTACGGTGTCCATATCGGCCAGTTAAGTCAGGATGATGAAGGCTATCTGTTTGA
ATACAAAAAATCCTATCTCGGCCCACCGCTATCATTGAGTTTACCGCTACAGACCGGAATATTTCGCAGCAAGTCATTAC
TGCCCTATTTCGCCTCGTTAGCCCCCGAAGGCTGGCTCCGACGACAGTACAGCCAGCTTCAACATCTGGATGAGAAGGAT
TTATTTGGCATCCTCATTCAAAACGGTAAGAACCTGATCGGCGCAGTACAACTAATCGCGGAGGATAAGTCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References