Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 135055..135610 Replicon chromosome
Accession NZ_CP024942
Organism Paraburkholderia terricola strain mHS1

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag CUJ90_RS19005 Protein ID WP_114163663.1
Coordinates 135055..135306 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag CUJ90_RS19010 Protein ID WP_114163664.1
Coordinates 135317..135610 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CUJ90_RS18990 130473..131360 - 888 WP_114163660.1 LysR family transcriptional regulator -
CUJ90_RS18995 131464..132384 + 921 WP_114163661.1 DMT family transporter -
CUJ90_RS19000 132839..134977 + 2139 WP_114163662.1 TonB-dependent siderophore receptor -
CUJ90_RS19005 135055..135306 - 252 WP_114163663.1 Txe/YoeB family addiction module toxin Toxin
CUJ90_RS19010 135317..135610 - 294 WP_114163664.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
CUJ90_RS19015 135953..136726 + 774 WP_073431923.1 GntR family transcriptional regulator -
CUJ90_RS19020 136735..138396 + 1662 WP_114163665.1 malonate decarboxylase subunit alpha -
CUJ90_RS19025 138399..139430 + 1032 WP_114163666.1 triphosphoribosyl-dephospho-CoA synthase -
CUJ90_RS19030 139418..139732 + 315 WP_073431925.1 malonate decarboxylase subunit delta -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-81)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9874.17 Da        Isoelectric Point: 7.1308

>T89306 WP_114163663.1 NZ_CP024942:c135306-135055 [Paraburkholderia terricola]
MFTDEAWDDYLYWQETDRKVLRKINTLLEECRRDPYSGTGKPEPLVGSLSGFWSRRITHGDRLVYLPRDGKIYVIACRFH
YGD

Download         Length: 252 bp

>T89306 NZ_CP024942:c135306-135055 [Paraburkholderia terricola]
ATGTTCACCGACGAAGCGTGGGACGACTATCTCTATTGGCAGGAAACCGACCGCAAGGTGCTGCGCAAGATCAACACGTT
GCTGGAGGAATGCCGGCGCGATCCTTATAGCGGTACGGGAAAGCCGGAGCCGCTGGTCGGCAGCTTGAGCGGCTTCTGGT
CGCGCCGCATCACGCATGGCGACCGTCTCGTCTACCTGCCGCGAGACGGAAAGATCTATGTGATTGCCTGCCGTTTTCAT
TACGGCGATTGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10662.04 Da        Isoelectric Point: 6.9790

>AT89306 WP_114163664.1 NZ_CP024942:c135610-135317 [Paraburkholderia terricola]
MNVLTYSEARAGFKQAMDEVCRDHTPMLITRQSGENVVMVSLDDFNAMQETLYLLSSSKNAQRLARSIAQLNAGGAAARE
LLTDEATEKPQRGSRKG

Download         Length: 294 bp

>AT89306 NZ_CP024942:c135610-135317 [Paraburkholderia terricola]
ATGAACGTCCTTACTTACAGCGAGGCGCGTGCCGGCTTCAAGCAAGCGATGGACGAAGTCTGCCGCGACCACACGCCCAT
GCTGATCACCCGGCAGAGCGGCGAAAACGTGGTCATGGTTTCGCTCGATGATTTCAATGCGATGCAGGAGACCTTGTATC
TGTTGAGTTCGTCGAAGAACGCCCAGCGGCTCGCTCGATCCATCGCCCAGTTGAACGCCGGCGGTGCGGCCGCGCGCGAA
CTGCTGACCGATGAAGCAACAGAAAAGCCGCAACGAGGAAGCCGCAAAGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References