Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/Tad-HTH_37
Location 98463..99069 Replicon chromosome
Accession NZ_CP024942
Organism Paraburkholderia terricola strain mHS1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag CUJ90_RS18850 Protein ID WP_114163642.1
Coordinates 98463..98795 (+) Length 111 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag CUJ90_RS18855 Protein ID WP_083086272.1
Coordinates 98782..99069 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CUJ90_RS18835 93578..95590 + 2013 WP_114163640.1 glycoside hydrolase family 28 protein -
CUJ90_RS18840 95696..96988 - 1293 WP_073430886.1 MFS transporter -
CUJ90_RS18845 97016..97849 - 834 WP_114163641.1 NAD(P)-dependent oxidoreductase -
CUJ90_RS18850 98463..98795 + 333 WP_114163642.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CUJ90_RS18855 98782..99069 + 288 WP_083086272.1 helix-turn-helix domain-containing protein Antitoxin
CUJ90_RS32410 99053..99301 - 249 WP_152035359.1 hypothetical protein -
CUJ90_RS18860 99396..100808 + 1413 WP_114163643.1 cytochrome ubiquinol oxidase subunit I -
CUJ90_RS18865 100845..101849 + 1005 WP_073430881.1 cytochrome d ubiquinol oxidase subunit II -
CUJ90_RS18870 101824..102009 + 186 WP_073430880.1 hypothetical protein -
CUJ90_RS18875 102340..103134 + 795 WP_083086274.1 response regulator transcription factor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(17-102)

Antitoxin

Cro/C1-type helix-turn-helix domain

(37-89)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 12437.66 Da        Isoelectric Point: 9.9009

>T89305 WP_114163642.1 NZ_CP024942:98463-98795 [Paraburkholderia terricola]
MALTIDFYNEKVKVNVASLPKTLLARFIALADRMEEYGPNLGEPHTASMGGGLFEMRLKGAEGIARVFYCAIVERKIVML
HCFVKKTQQTPRNELDVARKRLLEIRNGNL

Download         Length: 333 bp

>T89305 NZ_CP024942:98463-98795 [Paraburkholderia terricola]
ATGGCATTGACGATCGACTTCTACAACGAGAAGGTCAAAGTCAACGTCGCCTCGTTGCCGAAAACGCTGCTCGCGCGCTT
CATCGCGCTGGCCGACCGCATGGAGGAATACGGCCCGAATCTCGGCGAGCCGCACACCGCTTCAATGGGCGGCGGCTTGT
TCGAGATGCGCCTGAAAGGCGCGGAGGGAATCGCCAGAGTGTTCTACTGCGCAATCGTGGAACGGAAAATCGTCATGCTT
CACTGCTTCGTGAAGAAGACGCAACAAACGCCGCGCAACGAACTGGACGTGGCGCGCAAAAGACTACTGGAGATCAGAAA
TGGCAACCTATGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10623.17 Da        Isoelectric Point: 9.0172

>AT89305 WP_083086272.1 NZ_CP024942:98782-99069 [Paraburkholderia terricola]
MATYEAMRERALADPEVRAEYERLNREEFALLDQMLAARREAGLTQAQVAERMGTKAPAITRLERALASGRHSPSIDTLR
RYAAACGKQLFISIA

Download         Length: 288 bp

>AT89305 NZ_CP024942:98782-99069 [Paraburkholderia terricola]
ATGGCAACCTATGAGGCCATGCGCGAACGGGCGCTCGCCGACCCCGAAGTACGCGCCGAATATGAACGCCTCAACCGCGA
GGAATTCGCGCTGCTCGACCAGATGCTCGCGGCGCGCCGGGAGGCCGGCTTGACGCAGGCGCAAGTCGCCGAGCGCATGG
GCACGAAAGCACCGGCGATCACGCGGCTCGAACGGGCGCTGGCCTCGGGGCGGCACTCGCCTTCCATCGACACATTGCGC
AGGTACGCGGCCGCGTGCGGCAAGCAGTTGTTCATCTCGATCGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References