Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 1397901..1398601 Replicon chromosome
Accession NZ_CP024903
Organism Burkholderia pyrrocinia strain mHSR5

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag CUJ89_RS23820 Protein ID WP_114179858.1
Coordinates 1398305..1398601 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag CUJ89_RS23815 Protein ID WP_114179857.1
Coordinates 1397901..1398302 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CUJ89_RS23795 1393568..1394920 - 1353 WP_114179853.1 LLM class flavin-dependent oxidoreductase -
CUJ89_RS23800 1394928..1395977 - 1050 WP_114179854.1 LLM class flavin-dependent oxidoreductase -
CUJ89_RS23805 1396032..1396973 - 942 WP_114179855.1 ABC transporter substrate-binding protein -
CUJ89_RS23810 1397027..1397587 - 561 WP_114179856.1 GNAT family N-acetyltransferase -
CUJ89_RS23815 1397901..1398302 - 402 WP_114179857.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
CUJ89_RS23820 1398305..1398601 - 297 WP_114179858.1 type II toxin-antitoxin system MqsR family toxin Toxin
CUJ89_RS23825 1398704..1399744 - 1041 WP_114179859.1 succinylglutamate desuccinylase/aspartoacylase family protein -
CUJ89_RS23830 1399998..1400273 - 276 WP_114179860.1 hypothetical protein -
CUJ89_RS23835 1400534..1402084 - 1551 WP_114179861.1 sensor domain-containing diguanylate cyclase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Antitoxin MqsA

(3-131)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 10951.64 Da        Isoelectric Point: 8.0767

>T89236 WP_114179858.1 NZ_CP024903:c1398601-1398305 [Burkholderia pyrrocinia]
MEKGTPHCKLSRVKALVETGNVRLTASAVLGARQLGFTEREAIGVVMSLSAVDFHKSMTTYADHTIWQDVYQTRTVHGDV
YLKLTVIDDVLIVSFKER

Download         Length: 297 bp

>T89236 NZ_CP024903:c1398601-1398305 [Burkholderia pyrrocinia]
ATGGAAAAAGGAACGCCTCATTGCAAGCTGTCCCGGGTCAAGGCACTCGTCGAGACCGGCAACGTCCGCCTGACCGCGAG
TGCCGTACTGGGCGCGCGGCAACTGGGTTTCACGGAAAGGGAGGCGATCGGGGTCGTGATGTCGCTGAGTGCCGTCGATT
TCCACAAGAGCATGACGACCTACGCCGACCACACGATCTGGCAGGACGTCTATCAGACTCGTACCGTGCATGGCGACGTG
TACCTGAAGCTGACGGTGATCGACGATGTGCTGATCGTGTCTTTCAAGGAGCGTTGA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14599.00 Da        Isoelectric Point: 9.1878

>AT89236 WP_114179857.1 NZ_CP024903:c1398302-1397901 [Burkholderia pyrrocinia]
MKCPACGAAKLVRDTRDIPYTYKGRSTVIRGITGDFCPACGESVLDLDEATRLGEAASEFNKQVNASLVDPKFILKVRKK
LMLDQREAAELFGGGINAFSRYETGKTNPPLALVKLLKILDRHPYLLAEVRAA

Download         Length: 402 bp

>AT89236 NZ_CP024903:c1398302-1397901 [Burkholderia pyrrocinia]
ATGAAGTGCCCTGCATGCGGTGCTGCCAAGCTGGTCCGCGACACGCGCGACATCCCCTATACCTACAAGGGTCGATCGAC
GGTCATCCGCGGCATCACGGGCGATTTCTGTCCGGCCTGCGGAGAGTCCGTGCTGGATCTCGACGAAGCGACCCGGCTCG
GCGAGGCGGCAAGCGAATTCAACAAACAGGTGAACGCGAGTCTTGTCGATCCGAAGTTCATTCTGAAGGTCCGCAAGAAG
CTGATGCTGGATCAACGCGAGGCGGCCGAACTCTTCGGCGGCGGCATCAATGCGTTCTCTCGCTACGAGACCGGCAAGAC
GAACCCGCCGCTGGCCCTGGTGAAGCTGCTCAAGATACTCGACCGTCATCCGTATCTGCTGGCCGAAGTGCGGGCAGCGT
AG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References