Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/Gp49-HTH_37
Location 5270562..5270970 Replicon chromosome
Accession NZ_CP024901
Organism Photorhabdus laumondii subsp. laumondii strain TT01

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag PluTT01m_RS23135 Protein ID WP_082303157.1
Coordinates 5270842..5270970 (-) Length 43 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PluTT01m_RS23130 Protein ID WP_011148593.1
Coordinates 5270562..5270849 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PluTT01m_RS23110 5266661..5267716 + 1056 WP_011148589.1 hypothetical protein -
PluTT01m_RS23115 5267713..5269299 + 1587 WP_011148590.1 AMP-binding protein -
PluTT01m_RS23120 5269296..5269919 + 624 WP_011148591.1 CDP-alcohol phosphatidyltransferase family protein -
PluTT01m_RS23125 5269909..5270451 + 543 WP_011148592.1 CDP-archaeol synthase -
PluTT01m_RS23130 5270562..5270849 - 288 WP_011148593.1 helix-turn-helix domain-containing protein Antitoxin
PluTT01m_RS23135 5270842..5270970 - 129 WP_082303157.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PluTT01m_RS23140 5271134..5272279 - 1146 WP_011148594.1 ABC transporter permease -
PluTT01m_RS23145 5272279..5273424 - 1146 WP_011148595.1 ABC transporter permease -
PluTT01m_RS23150 5273432..5274403 - 972 WP_011148596.1 efflux RND transporter periplasmic adaptor subunit -
PluTT01m_RS23155 5274641..5275255 + 615 Protein_4432 ECF transporter S component -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(2-37)

Antitoxin

Cro/C1-type helix-turn-helix domain

(41-91)


Sequences

Toxin        


Download         Length: 43 a.a.        Molecular weight: 4960.83 Da        Isoelectric Point: 8.9777

>T89224 WP_082303157.1 NZ_CP024901:c5270970-5270842 [Photorhabdus laumondii subsp. laumondii]
IHYLFSQGKQVYILRCFVKKTDKTPPSEIELALKRLEDMTYG

Download         Length: 129 bp

>T89224 NZ_CP024901:c5270970-5270842 [Photorhabdus laumondii subsp. laumondii]
ATTCATTATCTTTTTTCACAAGGGAAGCAGGTTTACATTTTACGATGCTTTGTGAAGAAAACAGATAAAACACCACCATC
TGAAATAGAGTTAGCACTGAAACGATTGGAGGATATGACATATGGCTAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10724.44 Da        Isoelectric Point: 9.8357

>AT89224 WP_011148593.1 NZ_CP024901:c5270849-5270562 [Photorhabdus laumondii subsp. laumondii]
MAKVTPISHSEVRKRLLNTPEAIQAYVEATEEYELLEQLTEWREKAGLKKIDIAKRMGINPSAVTRIEKNVTKASWHTLK
RYAAACGVELSLTAK

Download         Length: 288 bp

>AT89224 NZ_CP024901:c5270849-5270562 [Photorhabdus laumondii subsp. laumondii]
ATGGCTAAAGTAACTCCTATCTCACATTCAGAAGTGAGAAAGCGACTTCTTAATACACCGGAAGCTATACAAGCCTATGT
TGAGGCTACAGAAGAATATGAGCTGCTGGAACAACTCACTGAGTGGCGGGAAAAGGCGGGTCTAAAGAAAATAGATATAG
CTAAACGGATGGGAATTAATCCGTCTGCGGTTACCCGTATTGAGAAGAATGTAACGAAAGCTAGTTGGCACACACTTAAA
CGTTATGCTGCTGCATGTGGTGTTGAGTTATCTTTAACTGCGAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References