Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 4489747..4490414 Replicon chromosome
Accession NZ_CP024900
Organism Photorhabdus laumondii subsp. laumondii strain DJC

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag PluDJC_RS19810 Protein ID WP_109791828.1
Coordinates 4489747..4490070 (+) Length 108 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PluDJC_RS19815 Protein ID WP_011148114.1
Coordinates 4490118..4490414 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PluDJC_RS19790 4486124..4487968 + 1845 WP_109791827.1 RNA polymerase sigma factor RpoD -
PluDJC_RS19805 4488791..4489363 - 573 WP_082302905.1 Bro-N domain-containing protein -
PluDJC_RS19810 4489747..4490070 + 324 WP_109791828.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PluDJC_RS19815 4490118..4490414 + 297 WP_011148114.1 helix-turn-helix domain-containing protein Antitoxin
PluDJC_RS25760 4490840..4491040 + 201 WP_125026254.1 hypothetical protein -
PluDJC_RS19820 4491428..4492354 - 927 WP_112872161.1 hypothetical protein -
PluDJC_RS19825 4492475..4493419 - 945 WP_109791830.1 class I SAM-dependent methyltransferase -
PluDJC_RS19830 4493557..4494091 - 535 Protein_3803 isopentenyl-diphosphate Delta-isomerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(34-106)

Antitoxin

Cro/C1-type helix-turn-helix domain

(39-92)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 12522.63 Da        Isoelectric Point: 10.1456

>T89186 WP_109791828.1 NZ_CP024900:4489747-4490070 [Photorhabdus laumondii subsp. laumondii]
MEYLVFIETPVFSKERAELLTDDEFRLLQEHLLKNHEQGSTISATGGCKKIRWQRERIGKRGGVRIIYYAITKTGRLYLL
LIYPKNKKDDLTPKEKEVLKAISNKLQ

Download         Length: 324 bp

>T89186 NZ_CP024900:4489747-4490070 [Photorhabdus laumondii subsp. laumondii]
ATGGAATATCTGGTTTTTATTGAAACTCCCGTATTTAGTAAAGAACGAGCAGAACTGTTAACCGATGATGAATTTAGGCT
ATTACAGGAGCACTTACTAAAGAATCACGAGCAGGGTAGTACCATCAGCGCTACTGGAGGATGTAAAAAGATTCGTTGGC
AGCGAGAAAGGATAGGAAAACGTGGCGGAGTAAGAATTATCTACTATGCCATAACCAAAACTGGGAGGCTCTATCTCCTT
TTGATTTACCCTAAAAATAAAAAAGATGACTTAACTCCAAAAGAAAAAGAGGTACTTAAAGCCATCAGTAACAAATTACA
GTAA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11269.92 Da        Isoelectric Point: 6.2274

>AT89186 WP_011148114.1 NZ_CP024900:4490118-4490414 [Photorhabdus laumondii subsp. laumondii]
MDKRLFNDLVESMNQMVAIEKGELSVFDENIHYHRLPDVKNLRETFGLKQSEFAEAVGVSTSLIQSWEQHRRIPSGSSLK
LLKMLERNPALINELSTL

Download         Length: 297 bp

>AT89186 NZ_CP024900:4490118-4490414 [Photorhabdus laumondii subsp. laumondii]
ATGGACAAAAGACTTTTTAACGATCTGGTTGAAAGCATGAATCAGATGGTAGCAATTGAAAAAGGCGAACTTTCTGTTTT
TGATGAAAATATCCATTACCATCGCCTGCCTGATGTAAAAAACTTACGTGAAACCTTTGGCTTAAAACAAAGTGAATTTG
CCGAAGCTGTTGGCGTTTCTACATCTCTAATTCAAAGCTGGGAACAGCACCGCCGCATTCCTTCTGGTTCATCACTGAAA
CTACTTAAGATGCTTGAACGTAATCCTGCGCTTATTAATGAATTAAGCACACTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References