Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 91467..92818 Replicon chromosome
Accession NZ_CP024842
Organism Pectobacterium versatile strain 3-2

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag OA04_RS00385 Protein ID WP_107332099.1
Coordinates 91467..92507 (-) Length 347 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag OA04_RS00390 Protein ID WP_107332100.1
Coordinates 92504..92818 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OA04_RS00360 88017..88304 - 288 WP_107332095.1 type II toxin-antitoxin system RelE/ParE family toxin -
OA04_RS00365 88301..88552 - 252 WP_010281712.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
OA04_RS00370 88809..89714 + 906 WP_107332096.1 siderophore-interacting protein -
OA04_RS00375 89749..90504 - 756 WP_107332097.1 thiol:disulfide interchange protein DsbG -
OA04_RS00380 90783..91406 + 624 WP_107332098.1 LysE family translocator -
OA04_RS00385 91467..92507 - 1041 WP_107332099.1 HipA domain-containing protein Toxin
OA04_RS00390 92504..92818 - 315 WP_107332100.1 HipA N-terminal domain-containing protein Antitoxin
OA04_RS00395 92803..93129 - 327 WP_103862833.1 helix-turn-helix domain-containing protein -
OA04_RS00400 93288..94160 - 873 WP_107332101.1 LysR family transcriptional regulator -
OA04_RS00405 94263..94772 + 510 WP_039542420.1 phenolic acid decarboxylase -
OA04_RS00410 94829..95962 - 1134 WP_107332102.1 alkylhydroperoxidase domain protein -
OA04_RS00415 95959..96993 - 1035 WP_107332103.1 putative FMN-dependent luciferase-like monooxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(57-307)

Antitoxin

HipA, N-terminal subdomain 1

(6-98)


Sequences

Toxin        


Download         Length: 347 a.a.        Molecular weight: 39637.69 Da        Isoelectric Point: 6.5017

>T88794 WP_107332099.1 NZ_CP024842:c92507-91467 [Pectobacterium versatile]
MKTCRILLTPLTHEEEMATGYSRKGLKHLAGSMHTSPDLRFTRQQFMHDLPQTQKGMSISGYQPKIQMVLQDRAFIVVDH
QGLYILKPSPIEFPHLAENEHATMTLMARLGFAVPPHGLLRFKPEQADDEPEFAFVIKRFDRDEKTGHPIHQEQLDGAMG
IGEKFGKIRADGRQYVSYERLALFLSEHVNDNIVFKIDLFRRIAYAYMLGNNDMHLRNFGLIHSRSGQLMLAPIYDFVSV
APYPTYFSSCFMALPLLIQEEGDEALAPGFETAYGEYLGMDFILFGQRIGLSEKLTKKLLADFIKEAECVESTYRDSFMP
AEAIDTTLRCYRHRLNLMSILDAERI

Download         Length: 1041 bp

>T88794 NZ_CP024842:c92507-91467 [Pectobacterium versatile]
ATGAAAACATGTCGAATTTTGCTGACACCGCTGACGCATGAAGAAGAGATGGCCACAGGTTATAGTCGTAAAGGTTTGAA
GCATCTGGCCGGGTCAATGCATACCTCTCCAGACTTACGTTTCACCCGCCAGCAATTCATGCACGACCTGCCACAAACAC
AGAAAGGCATGAGTATTTCTGGCTATCAGCCCAAGATTCAGATGGTGTTACAAGATCGGGCATTTATCGTCGTTGATCAT
CAAGGGCTGTACATTCTCAAACCCTCTCCGATTGAATTTCCCCATTTGGCAGAAAACGAACATGCCACGATGACGCTAAT
GGCACGCCTGGGATTTGCCGTCCCACCACACGGATTGCTCCGTTTTAAACCGGAGCAGGCTGATGACGAACCTGAGTTTG
CTTTCGTTATTAAGCGCTTCGACCGCGACGAAAAAACGGGCCACCCTATCCATCAGGAACAGTTGGACGGTGCGATGGGG
ATCGGGGAAAAATTCGGTAAAATACGAGCAGATGGAAGACAATACGTCAGTTATGAGCGGTTGGCTTTATTCCTTAGCGA
GCACGTAAATGACAATATCGTCTTCAAAATAGATCTGTTCCGCCGCATCGCTTACGCCTACATGCTGGGTAACAACGATA
TGCACCTGCGTAATTTTGGGCTGATACATTCGCGCTCAGGCCAATTAATGCTGGCCCCTATTTATGACTTTGTTTCCGTC
GCCCCCTATCCCACCTATTTTTCTTCCTGCTTCATGGCACTACCGCTGCTGATTCAAGAAGAGGGGGATGAAGCGCTCGC
ACCCGGCTTTGAAACCGCGTACGGAGAGTATCTGGGTATGGATTTCATTCTGTTCGGACAGCGTATCGGGCTGAGTGAAA
AGCTTACCAAAAAGCTACTGGCAGACTTCATCAAAGAAGCTGAATGCGTTGAATCAACCTATCGGGATTCCTTTATGCCT
GCGGAGGCGATTGATACGACGCTGCGGTGCTATCGACACCGCCTGAATCTTATGAGCATTCTCGATGCAGAACGGATTTA
G

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11768.48 Da        Isoelectric Point: 8.3628

>AT88794 WP_107332100.1 NZ_CP024842:c92818-92504 [Pectobacterium versatile]
VRRQVKVYLYGVHIGQLSQDDEGYLFEYKKSYIGPPLSLSLPIQTGTFRSKTLPPYFASLAPEGWLRRQYSQLQHLDEKD
LFGILIQNGKNLIGAVQLIAGDEA

Download         Length: 315 bp

>AT88794 NZ_CP024842:c92818-92504 [Pectobacterium versatile]
GTGCGCCGTCAAGTAAAGGTCTACCTTTACGGTGTCCATATCGGCCAGTTAAGTCAGGACGATGAAGGCTATCTGTTTGA
ATATAAAAAATCCTATATCGGCCCGCCATTATCCTTGAGCCTACCGATACAGACCGGAACATTTCGCAGCAAAACATTGC
CACCTTATTTTGCCTCGTTAGCCCCCGAAGGCTGGCTCCGGCGCCAGTACAGCCAGCTACAGCATCTGGATGAGAAAGAC
CTGTTTGGTATCCTCATTCAAAACGGTAAGAATCTGATCGGCGCCGTACAACTGATTGCAGGGGATGAAGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References