Detailed information of TA system TA088556

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-sprA1AS/-
• Location: 2520441..2520589
• Replicon: chromosome
• Accession: NZ_CP024809
• Organism: Staphylococcus haemolyticus strain 83131A

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: CUZ62_RS12785
• Protein ID: WP_011276848.1
• Coordinates: 2520494..2520589 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2520441..2520476 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CUZ62_RS12220	2516117..2516254	-	138	Protein_2346	NAD(P)H-dependent oxidoreductase	-
CUZ62_RS12225	2516396..2517526	-	1131	WP_033080168.1	NADH-dependent flavin oxidoreductase	-
CUZ62_RS12230	2517728..2518150	-	423	WP_033080167.1	MarR family transcriptional regulator	-
CUZ62_RS12235	2518794..2519396	-	603	WP_011276850.1	hypothetical protein	-
CUZ62_RS12240	2519608..2520300	-	693	WP_103416071.1	nucleotidyltransferase	-
-	2520441..2520476	-	36	-	-	Antitoxin
CUZ62_RS12785	2520494..2520589	-	96	WP_011276848.1	type I toxin-antitoxin system Fst family toxin	Toxin
CUZ62_RS12900	2520784..2520930	-	147	WP_000668388.1	hypothetical protein	-
CUZ62_RS12245	2521054..2521358	-	305	Protein_2353	hypothetical protein	-
CUZ62_RS12250	2521497..2521880	-	384	WP_011276846.1	effector binding domain-containing protein	-
CUZ62_RS12255	2522120..2522650	-	531	WP_011276845.1	N-acetyltransferase	-
CUZ62_RS12905	2523254..2523511	-	258	Protein_2356	replication initiation protein	-
CUZ62_RS12270	2524204..2524521	+	318	Protein_2357	IS200/IS605-like element ISSep3 family transposase	-
CUZ62_RS12275	2524629..2524862	-	234	WP_016931184.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	2524204..2524524	320

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3623.38 Da
• Isoelectric Point: 9.5124

>T88556 WP_011276848.1 NZ_CP024809:c2520589-2520494 [Staphylococcus haemolyticus]
MLEILVHITTTVISGCIIALFTHWLRNRKDK

Nucleotide

• Length: 96 bp

>T88556 NZ_CP024809:c2520589-2520494 [Staphylococcus haemolyticus]
ATGTTGGAAATCCTTGTTCACATCACGACCACAGTCATCAGTGGTTGTATTATTGCGTTATTTACGCATTGGCTGCGTAA
TCGCAAAGACAAATAG

Antitoxin

Nucleotide

• Length: 36 bp

>AT88556 NZ_CP024809:c2520476-2520441 [Staphylococcus haemolyticus]
TACAACAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin