Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 1525258..1525918 Replicon chromosome
Accession NZ_CP024780
Organism Pectobacterium brasiliense strain BZA12

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag CTV95_RS07060 Protein ID WP_100017156.1
Coordinates 1525565..1525918 (-) Length 118 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag CTV95_RS07055 Protein ID WP_010284412.1
Coordinates 1525258..1525560 (-) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CTV95_RS07030 1520370..1521806 - 1437 WP_100017152.1 glycoside hydrolase family 1 protein -
CTV95_RS07035 1522020..1522475 - 456 WP_100018499.1 helix-turn-helix domain-containing protein -
CTV95_RS07040 1522542..1523798 + 1257 WP_100017153.1 MFS transporter -
CTV95_RS07045 1523813..1524163 - 351 WP_014914858.1 helix-turn-helix domain-containing protein -
CTV95_RS07050 1524216..1525220 + 1005 WP_100017154.1 threonine/serine dehydratase -
CTV95_RS07055 1525258..1525560 - 303 WP_010284412.1 helix-turn-helix domain-containing protein Antitoxin
CTV95_RS07060 1525565..1525918 - 354 WP_100017156.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CTV95_RS07065 1526142..1526582 - 441 WP_039500392.1 helix-turn-helix transcriptional regulator -
CTV95_RS07070 1526685..1527296 + 612 WP_100017157.1 NAD(P)-dependent oxidoreductase -
CTV95_RS07075 1527462..1528301 + 840 WP_010284408.1 glutathione-dependent disulfide-bond oxidoreductase -
CTV95_RS07080 1528361..1529605 - 1245 WP_100017158.1 multidrug effflux MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-106)

Antitoxin

Cro/C1-type helix-turn-helix domain

(33-81)


Sequences

Toxin        


Download         Length: 118 a.a.        Molecular weight: 13592.75 Da        Isoelectric Point: 10.0465

>T88497 WP_100017156.1 NZ_CP024780:c1525918-1525565 [Pectobacterium brasiliense]
VWKIEMTDVFDSWFSTLNDRDRAYVLAALIVLREKGPMLSRPYADTVKGSRYFNMKELRIQSGGMPIRAFFAFDPHRTGI
LLCAGNKSGNEKRFYDEMIPLADREFTKYLKKSEKKG

Download         Length: 354 bp

>T88497 NZ_CP024780:c1525918-1525565 [Pectobacterium brasiliense]
GTGTGGAAAATTGAAATGACGGACGTGTTTGATAGCTGGTTCAGCACATTAAATGATAGGGATCGCGCATATGTGCTTGC
AGCACTTATCGTGTTACGGGAAAAAGGCCCAATGCTATCCAGGCCTTATGCTGATACGGTAAAAGGTTCCCGGTATTTCA
ACATGAAAGAATTACGTATTCAGAGCGGGGGGATGCCAATACGGGCATTTTTTGCTTTCGATCCACATCGCACGGGGATC
CTCCTCTGTGCGGGGAATAAGTCCGGCAATGAAAAGCGCTTTTATGATGAGATGATTCCGCTTGCCGATCGGGAATTCAC
AAAGTATCTGAAAAAATCAGAGAAGAAGGGGTAA

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 11107.90 Da        Isoelectric Point: 6.2283

>AT88497 WP_010284412.1 NZ_CP024780:c1525560-1525258 [Pectobacterium brasiliense]
MGRTLEQLLADEKPDVVVEAHAIAADMLLNIHLAELRERVQKTQVEMAQVLGLKQPTIAGMEKPGRDLKLSTLKRYVEAT
GSKLRLDVELPDGSHYGFTL

Download         Length: 303 bp

>AT88497 NZ_CP024780:c1525560-1525258 [Pectobacterium brasiliense]
ATGGGCAGAACGCTGGAACAGCTTCTTGCGGATGAAAAACCAGACGTCGTCGTTGAGGCTCACGCTATAGCGGCAGACAT
GTTACTCAATATTCATCTCGCCGAACTGCGTGAGAGGGTGCAAAAAACGCAAGTGGAAATGGCGCAGGTGCTTGGATTAA
AACAGCCAACCATTGCGGGAATGGAGAAACCCGGCCGCGATTTGAAACTTTCCACACTCAAACGCTATGTTGAGGCGACC
GGCAGTAAACTACGCCTTGATGTTGAACTGCCGGACGGTTCTCACTACGGGTTCACGCTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References