Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) yafN-yafO (relBE)/YafO-YafN
Location 2649708..2650402 Replicon chromosome
Accession NZ_CP024711
Organism Dickeya solani strain IFB 0099

Toxin (Protein)


Gene name yafO Uniprot ID -
Locus tag DSOL99_RS11850 Protein ID WP_026594479.1
Coordinates 2649708..2650106 (-) Length 133 a.a.

Antitoxin (Protein)


Gene name yafN Uniprot ID A0A2K8VUD1
Locus tag DSOL99_RS11855 Protein ID WP_022633740.1
Coordinates 2650109..2650402 (-) Length 98 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DSOL99_RS11820 2644888..2645922 - 1035 WP_022633732.1 harpin HrpZ family protein -
DSOL99_RS11825 2646083..2646493 - 411 WP_022633733.1 hypothetical protein -
DSOL99_RS11830 2646490..2646678 - 189 WP_022633734.1 hypothetical protein -
DSOL99_RS11835 2646713..2648782 - 2070 WP_023637836.1 type III secretion system outer membrane ring subunit SctC -
DSOL99_RS11840 2648775..2649209 - 435 WP_022633737.1 hypothetical protein -
DSOL99_RS11845 2649196..2649423 - 228 WP_022633738.1 type III secretion protein HrpF -
DSOL99_RS11850 2649708..2650106 - 399 WP_026594479.1 type II toxin-antitoxin system YafO family toxin Toxin
DSOL99_RS11855 2650109..2650402 - 294 WP_022633740.1 type I toxin-antitoxin system antitoxin YafN Antitoxin
DSOL99_RS11860 2650620..2651669 - 1050 WP_022633741.1 hypothetical protein -
DSOL99_RS11865 2652209..2653369 + 1161 WP_022633742.1 alpha/beta fold hydrolase -
DSOL99_RS11870 2653380..2654693 - 1314 WP_022633743.1 lytic murein transglycosylase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2649196..2659124 9928


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(27-130)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 133 a.a.        Molecular weight: 15230.56 Da        Isoelectric Point: 8.4931

>T88418 WP_026594479.1 NZ_CP024711:c2650106-2649708 [Dickeya solani]
IRIFKSTLIRQQLSQQELDDLVADFHAYKQNGVLPDTFGRDAPYDDDRTYPLVKAEQVAHIHLADADAPFPRFLRQFKRT
SDRAHLVYCQGAMDPEACLLIIILKPEAHKMARNNNNMHKIGMMAAAFRMKY

Download         Length: 399 bp

>T88418 NZ_CP024711:c2650106-2649708 [Dickeya solani]
ATACGGATTTTCAAGTCAACGCTGATCCGTCAACAATTGAGCCAGCAAGAGCTTGATGATTTGGTCGCGGATTTTCACGC
CTATAAGCAGAATGGGGTACTACCGGACACATTTGGGCGTGACGCGCCTTATGATGATGACCGAACCTATCCATTAGTAA
AAGCAGAGCAGGTGGCTCACATCCACCTTGCCGATGCGGATGCGCCTTTTCCCAGGTTCTTGCGCCAGTTCAAGAGAACC
AGCGATCGGGCCCATTTGGTCTACTGCCAGGGAGCGATGGATCCCGAGGCCTGCCTGTTAATTATTATTTTAAAACCCGA
AGCCCATAAAATGGCACGCAACAATAACAACATGCACAAGATCGGGATGATGGCCGCTGCGTTCAGGATGAAATATTGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10934.48 Da        Isoelectric Point: 5.2082

>AT88418 WP_022633740.1 NZ_CP024711:c2650402-2650109 [Dickeya solani]
MERILAEKSINITELRKNPAKYFIDEPVAVLSNNRPAGYMVSAKVFEELIDLLEAKQETVHTVARFRPTAERLRALADSG
QKLLNDASGKDLTEFTE

Download         Length: 294 bp

>AT88418 NZ_CP024711:c2650402-2650109 [Dickeya solani]
ATGGAGCGTATTCTTGCTGAAAAATCTATAAATATTACAGAGTTAAGGAAAAATCCGGCTAAGTATTTTATTGATGAGCC
TGTTGCCGTGCTTTCTAACAACCGGCCCGCCGGTTACATGGTGAGTGCCAAAGTCTTTGAAGAACTGATCGATCTGCTAG
AGGCGAAGCAGGAAACGGTTCATACCGTAGCGCGCTTTAGGCCAACGGCCGAACGTTTACGAGCCCTTGCAGATAGCGGT
CAGAAACTGCTGAATGATGCCTCTGGCAAGGATCTGACTGAGTTCACGGAATGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB A0A2K8VUD1

References