Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 324583..325187 Replicon chromosome
Accession NZ_CP024646
Organism Pseudomonas syringae isolate inb918

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag CT157_RS01405 Protein ID WP_127796616.1
Coordinates 324873..325187 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag CT157_RS01400 Protein ID WP_127796615.1
Coordinates 324583..324870 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CT157_RS01375 319616..320395 - 780 WP_007952688.1 EAL domain-containing protein -
CT157_RS01380 320512..320919 + 408 WP_007952687.1 RNA-binding protein S4 -
CT157_RS01385 320987..321787 - 801 WP_127796614.1 phosphatase PAP2 family protein -
CT157_RS01390 321892..322794 + 903 WP_085608616.1 Hsp33 family molecular chaperone HslO -
CT157_RS01395 322976..324517 + 1542 WP_007952682.1 phosphoenolpyruvate carboxykinase -
CT157_RS01400 324583..324870 - 288 WP_127796615.1 helix-turn-helix domain-containing protein Antitoxin
CT157_RS01405 324873..325187 - 315 WP_127796616.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CT157_RS01410 325299..325598 - 300 WP_115076187.1 hypothetical protein -
CT157_RS01415 326149..327276 - 1128 WP_127800796.1 hypothetical protein -
CT157_RS01420 327379..327660 - 282 WP_205891534.1 hypothetical protein -
CT157_RS01425 327965..328468 + 504 WP_007952668.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(42-100)

Antitoxin

Cro/C1-type helix-turn-helix domain

(35-86)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11859.76 Da        Isoelectric Point: 10.2570

>T88141 WP_127796616.1 NZ_CP024646:c325187-324873 [Pseudomonas syringae]
MIFVETRIFTRRVKELLDDDTYAAFQKQLVVSPSIGDVIEGTGGIRKTRIAAKGYGKRGGARVIYYHFVSASQIGLLMIY
PKNEQHDLSSDERKALKVLIEKWR

Download         Length: 315 bp

>T88141 NZ_CP024646:c325187-324873 [Pseudomonas syringae]
ATGATTTTTGTTGAGACTCGGATCTTTACCCGTCGAGTAAAAGAGCTGCTGGACGATGACACGTATGCCGCTTTTCAGAA
GCAACTGGTTGTAAGTCCTTCGATTGGCGATGTAATTGAAGGTACAGGCGGGATCCGCAAAACCCGAATCGCAGCGAAAG
GATACGGCAAGCGAGGCGGAGCACGGGTGATCTACTACCACTTCGTTTCGGCGTCACAAATCGGGTTATTGATGATCTAC
CCTAAAAATGAACAACACGATCTGTCCAGCGATGAGCGTAAAGCACTCAAGGTCTTGATCGAAAAATGGAGATGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10746.33 Da        Isoelectric Point: 7.4052

>AT88141 WP_127796615.1 NZ_CP024646:c324870-324583 [Pseudomonas syringae]
MSKFFDELMESVQEMDEIVRGQRAPSREFHVDALQVKEIRKATGLTQTKFAALIDVQLGTLRNWEQGRREPTGPAKALLK
AIHNDPVHVLNALAH

Download         Length: 288 bp

>AT88141 NZ_CP024646:c324870-324583 [Pseudomonas syringae]
ATGAGCAAATTTTTTGATGAGCTGATGGAAAGTGTGCAAGAGATGGACGAGATTGTACGAGGCCAGCGCGCACCTTCTCG
CGAATTCCACGTTGATGCATTGCAGGTCAAAGAGATTCGTAAAGCTACCGGTTTGACCCAGACCAAATTTGCGGCTCTGA
TCGACGTCCAACTCGGCACTCTACGAAATTGGGAACAGGGTCGTCGCGAGCCTACCGGGCCGGCAAAAGCTTTGCTCAAG
GCCATTCATAACGACCCGGTTCATGTTTTGAATGCATTGGCCCATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References