Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 1592919..1593410 Replicon chromosome
Accession NZ_CP024412
Organism Glaesserella parasuis strain SH0104

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag CRH16_RS08195 Protein ID WP_015940086.1
Coordinates 1592919..1593155 (+) Length 79 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag CRH16_RS08200 Protein ID WP_075605398.1
Coordinates 1593207..1593410 (+) Length 68 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CRH16_RS08160 1588035..1590164 + 2130 WP_112063077.1 cadmium-translocating P-type ATPase -
CRH16_RS08170 1590647..1592085 - 1439 Protein_1527 glutamate--tRNA ligase -
CRH16_RS08195 1592919..1593155 + 237 WP_015940086.1 hypothetical protein Toxin
CRH16_RS08200 1593207..1593410 + 204 WP_075605398.1 hypothetical protein Antitoxin
CRH16_RS08205 1593611..1594771 + 1161 WP_035520425.1 bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN -
CRH16_RS08210 1594815..1595786 - 972 WP_012621529.1 IS110 family transposase -
CRH16_RS08215 1596026..1596607 + 582 WP_010786056.1 type IV pilus biogenesis/stability protein PilW -
CRH16_RS08220 1596669..1597604 + 936 WP_112063078.1 KpsF/GutQ family sugar-phosphate isomerase -
CRH16_RS08225 1597604..1598092 + 489 WP_005710400.1 transcription elongation factor GreB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin YafO

(27-130)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 79 a.a.        Molecular weight: 9226.74 Da        Isoelectric Point: 10.0402

>T87619 WP_015940086.1 NZ_CP024412:1592919-1593155 [Glaesserella parasuis]
MNVTFVELPPFEEYRKKYLDDDTFRLLQNELLKFPDKGELIQGTGGLRKLRIVDIIRQKGKRGGARVIYYYYVQGKQV

Download         Length: 237 bp

>T87619 NZ_CP024412:1592919-1593155 [Glaesserella parasuis]
ATGAATGTCACTTTTGTGGAATTACCGCCTTTTGAGGAATATAGAAAAAAGTATCTTGACGATGACACATTTAGATTATT
ACAAAATGAGTTATTAAAATTTCCCGATAAGGGAGAGCTTATTCAAGGTACTGGGGGACTAAGAAAATTGCGTATTGTAG
ATATTATTAGACAAAAAGGAAAAAGAGGCGGAGCTAGGGTAATCTATTACTATTATGTGCAAGGGAAACAAGTTTAG

Antitoxin


Download         Length: 68 a.a.        Molecular weight: 7467.98 Da        Isoelectric Point: 8.7090

>AT87619 WP_075605398.1 NZ_CP024412:1593207-1593410 [Glaesserella parasuis]
MEGMQALELHLKGKITLKTTVVEVPDPIVITPEEVKAIRQKLNLSQAVLLLKMVEKSPKTFEQIASI

Download         Length: 204 bp

>AT87619 NZ_CP024412:1593207-1593410 [Glaesserella parasuis]
ATGGAAGGGATGCAAGCATTAGAGTTGCATTTAAAAGGCAAAATCACACTAAAAACCACTGTCGTAGAAGTTCCCGATCC
GATAGTAATTACCCCTGAAGAAGTGAAAGCCATTCGCCAAAAATTAAATCTTTCACAAGCGGTTTTATTATTAAAAATGG
TTGAGAAATCACCAAAAACATTTGAGCAAATTGCGAGCATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References