Detailed information of TA system TA087520

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): symE-agrB/SymE(toxin)
• Location: 735102..735514
• Replicon: chromosome
• Accession: NZ_CP024282
• Organism: Escherichia albertii strain 2014C-4356

Toxin (Protein)

• Gene name: symE
• Uniprot ID: A0A8D9PK47
• Locus tag: CCF14_RS03790
• Protein ID: WP_000132619.1
• Coordinates: 735173..735514 (+)
• Length: 114 a.a.

Antitoxin (RNA)

Gene name	agrB
Locus tag	-
Coordinates	735102..735178 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CCF14_RS03780	731974..733563	+	1590	WP_059257976.1	type I restriction-modification system methyltransferase	-
CCF14_RS03785	733560..734945	+	1386	WP_059257978.1	restriction endonuclease subunit S	-
-	735102..735178	-	77	NuclAT_6	-	Antitoxin
-	735102..735178	-	77	NuclAT_6	-	Antitoxin
-	735102..735178	-	77	NuclAT_6	-	Antitoxin
-	735102..735178	-	77	NuclAT_6	-	Antitoxin
-	735102..735178	-	77	NuclAT_7	-	Antitoxin
-	735102..735178	-	77	NuclAT_7	-	Antitoxin
-	735102..735178	-	77	NuclAT_7	-	Antitoxin
-	735102..735178	-	77	NuclAT_7	-	Antitoxin
CCF14_RS03790	735173..735514	+	342	WP_000132619.1	endoribonuclease SymE	Toxin
CCF14_RS03795	735676..737054	+	1379	Protein_702	5-methylcytosine-specific restriction endonuclease subunit McrB	-
CCF14_RS03800	737054..738100	+	1047	WP_015953744.1	5-methylcytosine-specific restriction endonuclease system specificity protein McrC	-
CCF14_RS03805	738156..738884	-	729	Protein_704	DUF1998 domain-containing protein	-
CCF14_RS03810	739551..740483	-	933	WP_059257983.1	Rpn family recombination-promoting nuclease/putative transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin SymE-like (20-71)

Sequences

Toxin

Protein

• Length: 114 a.a.
• Molecular weight: 12322.13 Da
• Isoelectric Point: 7.8219

>T87520 WP_000132619.1 NZ_CP024282:735173-735514 [Escherichia albertii]
MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTAVDVKVMEGCIVLTAQPPAPEESE
LMQSLRQVCKLSARKQKQVQEFIGVIAGKQKVA

Nucleotide

• Length: 342 bp

>T87520 NZ_CP024282:735173-735514 [Escherichia albertii]
ATGACTGACACGCATTCTATTGCACAACCGTTCGAAGCAGAAGTCTCCCCGGCAAATAACCGTCAATTAACCGTGAGTTA
TGCGAGTCGCTACCCGGATTACAGCCGTATTCCCGCCATCACCCTGAAAGGTCAGTGGCTGGAAGCCGCCGGTTTTGCCA
CCGGCACGGCGGTAGATGTCAAAGTGATGGAAGGCTGTATTGTCCTCACCGCCCAACCACCCGCCCCCGAAGAGAGCGAA
CTGATGCAGTCGCTACGCCAGGTGTGCAAGCTGTCGGCGCGTAAACAGAAGCAGGTGCAGGAGTTTATTGGGGTGATTGC
CGGTAAACAGAAAGTCGCGTAA

Antitoxin

Nucleotide

• Length: 77 bp

>AT87520 NZ_CP024282:c735178-735102 [Escherichia albertii]
AGTCATAACTGCTATTCTCCGATAATAGTGATTGTGATGAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Structures

Antitoxin