Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 610447..610705 Replicon chromosome
Accession NZ_CP024282
Organism Escherichia albertii strain 2014C-4356

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag CCF14_RS03090 Protein ID WP_000809168.1
Coordinates 610553..610705 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 610447..610504 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CCF14_RS03070 606255..607502 - 1248 WP_099587770.1 cytoplasmic protein -
CCF14_RS03075 607656..609149 - 1494 WP_059216552.1 sulfatase-like hydrolase/transferase -
CCF14_RS03080 609170..609931 - 762 WP_099587771.1 hypothetical protein -
- 610447..610504 - 58 - - Antitoxin
CCF14_RS03090 610553..610705 + 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
CCF14_RS03095 610783..611895 + 1113 WP_001300563.1 IS4-like element IS421 family transposase -
CCF14_RS03105 612158..613288 - 1131 WP_001118445.1 molecular chaperone DnaJ -
CCF14_RS03110 613377..615293 - 1917 WP_000516135.1 molecular chaperone DnaK -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T87518 WP_000809168.1 NZ_CP024282:610553-610705 [Escherichia albertii]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

>T87518 NZ_CP024282:610553-610705 [Escherichia albertii]
ATGAAGCAGCATAAGGCGATGATTGTCGCCCTGATCGTCATCTGTATCACCGCCGTAGTGGCGGCGCTGGTAACGAGAAA
AGACCTCTGTGAGGTTCACATCCGAACTGGCCAGACGGAGGTTGCTGTCTTCACGGCTTACGAATCCGAGTAA

Antitoxin


Download         Length: 58 bp

>AT87518 NZ_CP024282:c610504-610447 [Escherichia albertii]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References