Detailed information of TA system TA086683

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mqsRA (relBE)/MqsR-MqsA
• Location: 4197803..4198503
• Replicon: chromosome
• Accession: NZ_CP024085
• Organism: Pseudomonas putida strain E41

Toxin (Protein)

• Gene name: mqsR
• Uniprot ID: -
• Locus tag: CR511_RS18955
• Protein ID: WP_027592890.1
• Coordinates: 4198207..4198503 (-)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: mqsA
• Uniprot ID: A0A2D1TJ12
• Locus tag: CR511_RS18950
• Protein ID: WP_027592889.1
• Coordinates: 4197803..4198204 (-)
• Length: 134 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CR511_RS18935	4193830..4194759	-	930	WP_027592886.1	FAD-binding protein	-
CR511_RS18940	4194760..4195509	-	750	WP_027592887.1	electron transfer flavoprotein subunit beta/FixA family protein	-
CR511_RS18945	4196048..4197730	+	1683	WP_081717456.1	electron transfer flavoprotein-ubiquinone oxidoreductase	-
CR511_RS18950	4197803..4198204	-	402	WP_027592889.1	type II toxin-antitoxin system MqsA family antitoxin	Antitoxin
CR511_RS18955	4198207..4198503	-	297	WP_027592890.1	type II toxin-antitoxin system MqsR family toxin	Toxin
CR511_RS18960	4198598..4199923	-	1326	WP_099454840.1	MFS transporter	-
CR511_RS18965	4199996..4200475	-	480	WP_099454841.1	histidine kinase	-
CR511_RS18970	4200645..4201121	-	477	WP_099454842.1	sigma-70 family RNA polymerase sigma factor	-
CR511_RS18975	4201352..4202524	+	1173	WP_099454843.1	efflux RND transporter periplasmic adaptor subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase toxin MqsR (5-97)

Antitoxin

• Antitoxin MqsA (3-131)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 11352.19 Da
• Isoelectric Point: 8.8385

>T86683 WP_027592890.1 NZ_CP024085:c4198503-4198207 [Pseudomonas putida]
MEKRTPHCPLQRIRALVSAGRISPTTASLRDAQALGMEYPDMLDVINGLERRDFYKSMTSYVDHRVWQDVYRPLTVKGYV
YLKLSVVDDVLIVSFKEM

Nucleotide

• Length: 297 bp

>T86683 NZ_CP024085:c4198503-4198207 [Pseudomonas putida]
ATGGAAAAGAGAACGCCTCACTGTCCGCTGCAGCGGATAAGGGCATTGGTCAGTGCTGGACGTATCAGCCCGACTACCGC
CTCGTTGCGAGACGCCCAGGCACTGGGGATGGAATACCCGGATATGCTCGATGTCATCAATGGCTTGGAGCGCAGAGACT
TTTACAAAAGCATGACCAGCTACGTTGATCATCGCGTTTGGCAGGATGTTTATCGTCCGCTTACGGTCAAGGGGTACGTG
TACCTCAAACTGTCTGTGGTGGACGACGTTCTCATCGTGTCTTTCAAGGAGATGTAA

Antitoxin

Protein

• Length: 134 a.a.
• Molecular weight: 14593.61 Da
• Isoelectric Point: 5.2321

>AT86683 WP_027592889.1 NZ_CP024085:c4198204-4197803 [Pseudomonas putida]
MRCPICGGAELAPDTQDMPYRYKGEATLIPNVSGDYCAACGEAVLSHDEALRISDLMSAFNRQVNAAAVDPGFIVSVRKK
FDLDQREAGEIFGGGVNAFSRYENGKTRPPVALVKLFKLLDRHPELFEEVRTA

Nucleotide

• Length: 402 bp

>AT86683 NZ_CP024085:c4198204-4197803 [Pseudomonas putida]
ATGAGATGTCCAATCTGCGGCGGTGCGGAGCTTGCGCCCGACACTCAGGACATGCCCTATCGATACAAGGGTGAAGCGAC
CCTTATTCCGAATGTCAGTGGCGACTACTGTGCTGCCTGTGGTGAGGCAGTGCTGAGCCATGATGAAGCTTTGCGCATCA
GTGACCTGATGTCGGCGTTCAATCGCCAGGTCAACGCTGCGGCGGTCGACCCGGGCTTCATCGTCTCAGTGCGCAAGAAA
TTCGATCTCGACCAGCGTGAAGCAGGGGAGATCTTCGGGGGTGGCGTCAATGCGTTCTCCCGTTACGAAAACGGTAAAAC
CAGGCCACCCGTGGCGTTGGTCAAACTGTTCAAACTGCTGGATCGCCACCCGGAACTGTTCGAAGAAGTACGCACTGCCT
GA

Structures

Antitoxin

• AlphaFold DB: A0A2D1TJ12