Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/HigB-HigA |
Location | 1314110..1314696 | Replicon | chromosome |
Accession | NZ_CP024085 | ||
Organism | Pseudomonas putida strain E41 |
Toxin (Protein)
Gene name | graT | Uniprot ID | - |
Locus tag | CR511_RS05955 | Protein ID | WP_099453131.1 |
Coordinates | 1314418..1314696 (-) | Length | 93 a.a. |
Antitoxin (Protein)
Gene name | graA | Uniprot ID | - |
Locus tag | CR511_RS05950 | Protein ID | WP_099453130.1 |
Coordinates | 1314110..1314409 (-) | Length | 100 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CR511_RS05925 | 1310052..1310861 | + | 810 | WP_027595781.1 | tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA | - |
CR511_RS05930 | 1310871..1311281 | - | 411 | WP_099453128.1 | SufE family protein | - |
CR511_RS05935 | 1311278..1312483 | - | 1206 | WP_099453129.1 | cysteine desulfurase | - |
CR511_RS05940 | 1312562..1313596 | - | 1035 | WP_027595784.1 | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase | - |
CR511_RS05945 | 1313638..1313985 | - | 348 | WP_027595785.1 | ArsC family reductase | - |
CR511_RS05950 | 1314110..1314409 | - | 300 | WP_099453130.1 | HigA family addiction module antidote protein | Antitoxin |
CR511_RS05955 | 1314418..1314696 | - | 279 | WP_099453131.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
CR511_RS05960 | 1314939..1316585 | + | 1647 | WP_085272745.1 | Na+/H+ antiporter | - |
CR511_RS05965 | 1316851..1318047 | - | 1197 | WP_099453132.1 | succinyldiaminopimelate transaminase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10491.80 Da Isoelectric Point: 7.1347
>T86681 WP_099453131.1 NZ_CP024085:c1314696-1314418 [Pseudomonas putida]
MIQAFSCADTEALFTTGKTRRWSDIKSVAERKLTMLDAATELRDLRSPPGNRLEQLSGNRAGQHSIRVNDQWRVCFIWTE
NGPANVEIVDYH
MIQAFSCADTEALFTTGKTRRWSDIKSVAERKLTMLDAATELRDLRSPPGNRLEQLSGNRAGQHSIRVNDQWRVCFIWTE
NGPANVEIVDYH
Download Length: 279 bp
>T86681 NZ_CP024085:c1314696-1314418 [Pseudomonas putida]
ATGATTCAAGCCTTCAGCTGTGCTGACACGGAAGCACTCTTCACGACTGGAAAGACACGGCGTTGGTCAGATATCAAATC
TGTCGCAGAGCGCAAATTGACCATGCTTGATGCTGCCACAGAACTGCGCGACCTTCGCTCTCCTCCGGGCAATCGCCTGG
AACAGTTGAGCGGTAATCGCGCCGGCCAACACAGCATACGAGTCAATGATCAGTGGCGCGTGTGCTTTATCTGGACGGAA
AACGGTCCGGCAAACGTTGAAATTGTCGATTACCACTGA
ATGATTCAAGCCTTCAGCTGTGCTGACACGGAAGCACTCTTCACGACTGGAAAGACACGGCGTTGGTCAGATATCAAATC
TGTCGCAGAGCGCAAATTGACCATGCTTGATGCTGCCACAGAACTGCGCGACCTTCGCTCTCCTCCGGGCAATCGCCTGG
AACAGTTGAGCGGTAATCGCGCCGGCCAACACAGCATACGAGTCAATGATCAGTGGCGCGTGTGCTTTATCTGGACGGAA
AACGGTCCGGCAAACGTTGAAATTGTCGATTACCACTGA
Antitoxin
Download Length: 100 a.a. Molecular weight: 10901.60 Da Isoelectric Point: 5.6714
>AT86681 WP_099453130.1 NZ_CP024085:c1314409-1314110 [Pseudomonas putida]
MLKNGMRPIHPGEVLREDFQKEMGFSAAALARALGVATPTVNNILRERGGISADMALRLAICLDTTPEFWLNLQIAFDLR
TAEQQHGDEIIASVQRLVA
MLKNGMRPIHPGEVLREDFQKEMGFSAAALARALGVATPTVNNILRERGGISADMALRLAICLDTTPEFWLNLQIAFDLR
TAEQQHGDEIIASVQRLVA
Download Length: 300 bp
>AT86681 NZ_CP024085:c1314409-1314110 [Pseudomonas putida]
ATGCTCAAGAATGGCATGCGTCCAATACATCCTGGTGAAGTTCTGCGCGAGGACTTCCAGAAAGAAATGGGGTTCAGTGC
CGCTGCTCTGGCGCGGGCATTGGGTGTTGCGACGCCAACGGTCAACAACATCCTGCGCGAGCGTGGCGGCATTTCCGCCG
ACATGGCACTGCGCCTGGCCATCTGCCTGGATACCACACCGGAGTTCTGGCTCAACCTGCAAATCGCCTTCGATTTGCGC
ACAGCCGAACAGCAACATGGCGATGAGATCATCGCATCCGTGCAGCGCTTGGTCGCTTGA
ATGCTCAAGAATGGCATGCGTCCAATACATCCTGGTGAAGTTCTGCGCGAGGACTTCCAGAAAGAAATGGGGTTCAGTGC
CGCTGCTCTGGCGCGGGCATTGGGTGTTGCGACGCCAACGGTCAACAACATCCTGCGCGAGCGTGGCGGCATTTCCGCCG
ACATGGCACTGCGCCTGGCCATCTGCCTGGATACCACACCGGAGTTCTGGCTCAACCTGCAAATCGCCTTCGATTTGCGC
ACAGCCGAACAGCAACATGGCGATGAGATCATCGCATCCGTGCAGCGCTTGGTCGCTTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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