Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4755904..4756558 Replicon chromosome
Accession NZ_CP024025
Organism Pseudomonas protegens strain DTU9.1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag CLA18_RS21480 Protein ID WP_053152689.1
Coordinates 4755904..4756254 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag CLA18_RS21485 Protein ID WP_265577288.1
Coordinates 4756241..4756558 (+) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CLA18_RS21470 (CLA18_21395) 4752663..4754195 + 1533 WP_015636298.1 NADH-quinone oxidoreductase subunit M -
CLA18_RS21475 (CLA18_21400) 4754203..4755666 + 1464 WP_015636299.1 NADH-quinone oxidoreductase subunit NuoN -
CLA18_RS21480 (CLA18_21405) 4755904..4756254 + 351 WP_053152689.1 hypothetical protein Toxin
CLA18_RS21485 (CLA18_21410) 4756241..4756558 + 318 WP_265577288.1 transcriptional regulator Antitoxin
CLA18_RS21490 (CLA18_21415) 4756627..4758009 - 1383 WP_265577289.1 cysteine--tRNA ligase -
CLA18_RS21495 (CLA18_21420) 4758028..4759728 - 1701 WP_210458375.1 glutamine--tRNA ligase/YqeY domain fusion protein -
CLA18_RS21500 (CLA18_21425) 4759999..4760502 + 504 WP_011062201.1 peptidylprolyl isomerase -
CLA18_RS21505 (CLA18_21430) 4760499..4761251 + 753 WP_011062202.1 UDP-2,3-diacylglucosamine diphosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(48-101)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13936.07 Da        Isoelectric Point: 9.6226

>T86590 WP_053152689.1 NZ_CP024025:4755904-4756254 [Pseudomonas protegens]
MNALFIELPAFARYRKGFLDDELFCELQIELLRHPHAGVLIQGTGGLRKMRFIDERRNKGRRGGLRVIYYWWSGGAQFWL
FTLFDKEQMDDLLPQQRQQLKQLLEREIEARRHDQT

Download         Length: 351 bp

>T86590 NZ_CP024025:4755904-4756254 [Pseudomonas protegens]
ATGAATGCTCTGTTTATTGAACTACCGGCATTTGCGCGATACCGAAAGGGCTTCCTTGACGACGAATTGTTCTGCGAACT
GCAGATCGAGTTGCTGCGCCACCCGCACGCGGGCGTTCTGATTCAGGGCACTGGCGGCTTGCGCAAGATGCGTTTCATCG
ATGAGCGACGCAACAAGGGCAGGCGTGGCGGGCTGAGGGTGATTTATTACTGGTGGTCCGGAGGAGCACAGTTCTGGCTC
TTCACCCTGTTCGACAAGGAGCAGATGGACGACCTGCTACCGCAGCAGCGACAACAGCTCAAACAACTGCTGGAACGTGA
AATCGAGGCCAGAAGACATGACCAAACGTGA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 12080.95 Da        Isoelectric Point: 10.4439

>AT86590 WP_265577288.1 NZ_CP024025:4756241-4756558 [Pseudomonas protegens]
MTKRDIFSELVEGIDALTQERQGKITLRSHKVKLDKLPPITAAEVMNIRQQLNLSRSVFAMYLRTNTRTLENWEQGRAIP
NTQATTLIRLVERYPDTVERLASLA

Download         Length: 318 bp

>AT86590 NZ_CP024025:4756241-4756558 [Pseudomonas protegens]
ATGACCAAACGTGACATCTTTTCCGAACTGGTTGAAGGCATCGACGCCCTCACCCAGGAACGCCAGGGCAAGATCACCCT
GCGCAGCCATAAAGTGAAACTCGACAAGCTGCCCCCCATCACCGCCGCCGAGGTGATGAACATCCGCCAGCAACTCAACC
TCTCGCGCTCGGTGTTCGCCATGTACCTGCGCACCAACACCCGCACCCTGGAGAACTGGGAACAGGGCCGCGCCATACCC
AACACCCAGGCCACGACCTTGATACGCCTGGTGGAGCGCTACCCCGATACAGTGGAGCGCCTCGCCTCGCTGGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References