Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 850581..850743 Replicon chromosome
Accession NZ_CP023966
Organism Staphylococcus capitis strain FDAARGOS_378

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A507SQ11
Locus tag CRN29_RS04215 Protein ID WP_030063529.1
Coordinates 850581..850685 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 850713..850743 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CRN29_RS04205 846513..849452 + 2940 WP_049326519.1 AAA family ATPase -
CRN29_RS04210 849449..850390 + 942 WP_002434737.1 3'-5' exoribonuclease YhaM -
CRN29_RS04215 850581..850685 + 105 WP_030063529.1 type I toxin-antitoxin system Fst family toxin Toxin
- 850713..850743 + 31 - - Antitoxin
CRN29_RS04220 850840..851841 - 1002 WP_023350053.1 peptidylprolyl isomerase -
CRN29_RS04225 852043..852612 - 570 WP_002434864.1 DUF3267 domain-containing protein -
CRN29_RS04230 852804..853175 - 372 WP_002434824.1 YtxH domain-containing protein -
CRN29_RS04235 853253..853678 - 426 WP_002434751.1 HIT family protein -
CRN29_RS04240 853811..854551 + 741 WP_002453567.1 ABC transporter ATP-binding protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 35 a.a.        Molecular weight: 3963.74 Da        Isoelectric Point: 10.7588

>T86541 WP_030063529.1 NZ_CP023966:850581-850685 [Staphylococcus capitis]
MLFDIFVHIMATATSGCIVALFAHWLRTRNDKRK

Download         Length: 105 bp

>T86541 NZ_CP023966:850581-850685 [Staphylococcus capitis]
ATGTTATTTGATATCTTTGTACACATCATGGCCACGGCAACCAGTGGTTGTATCGTTGCTTTATTCGCGCATTGGCTACG
CACTCGCAACGATAAACGTAAATAG

Antitoxin


Download         Length: 31 bp

>AT86541 NZ_CP023966:850713-850743 [Staphylococcus capitis]
AAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A507SQ11


Antitoxin

Download structure file

References