Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 1463527..1464342 Replicon chromosome
Accession NZ_CP023965
Organism Proteus vulgaris strain FDAARGOS_366

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag CRN77_RS06530 Protein ID WP_098941857.1
Coordinates 1463527..1464000 (-) Length 158 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag CRN77_RS06535 Protein ID WP_098941858.1
Coordinates 1464007..1464342 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CRN77_RS06515 1459349..1461544 - 2196 WP_098941854.1 hypothetical protein -
CRN77_RS06520 1461631..1462266 - 636 WP_098941855.1 DUF1449 family protein -
CRN77_RS06525 1462569..1463216 - 648 WP_098941856.1 CPBP family intramembrane metalloprotease -
CRN77_RS06530 1463527..1464000 - 474 WP_098941857.1 type II toxin-antitoxin system YhaV family toxin Toxin
CRN77_RS06535 1464007..1464342 - 336 WP_098941858.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
CRN77_RS06545 1464990..1465562 - 573 WP_098941859.1 transcriptional regulator -
CRN77_RS06550 1465745..1467070 - 1326 WP_098941860.1 anaerobic C4-dicarboxylate transporter -
CRN77_RS06555 1467229..1468653 - 1425 WP_072069056.1 aspartate ammonia-lyase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(12-147)

Antitoxin

PrlF antitoxin

(15-109)


Sequences

Toxin        


Download         Length: 158 a.a.        Molecular weight: 18605.24 Da        Isoelectric Point: 9.2715

>T86535 WP_098941857.1 NZ_CP023965:c1464000-1463527 [Proteus vulgaris]
MDFPTDLNGWTIYAHPCFKQQYDELLQKVEALKKKYPEDYQKKADTKIFAHVLKSIVNITNDPRAPELRLGNTLGEENKN
WSRIKLVNGRYRLFFRFSFKEKIIILAWINDNDTLRTYGNKTDAYRVFEKKLKKGHPPKNWNDLFSDCINEADCQDP

Download         Length: 474 bp

>T86535 NZ_CP023965:c1464000-1463527 [Proteus vulgaris]
ATGGATTTCCCTACAGATTTGAATGGATGGACAATCTACGCACATCCTTGCTTTAAACAACAATATGATGAATTACTACA
AAAAGTCGAAGCTCTGAAAAAAAAATATCCCGAAGATTATCAGAAAAAAGCAGATACAAAAATTTTTGCTCATGTATTGA
AATCTATAGTAAACATCACAAATGACCCACGGGCACCAGAGCTTAGGTTGGGTAATACTTTAGGAGAAGAAAATAAAAAT
TGGTCACGAATTAAATTAGTAAATGGAAGATATCGTTTATTTTTTAGATTCAGTTTTAAGGAAAAGATCATCATTCTGGC
ATGGATAAATGATAATGATACTTTGCGAACTTATGGCAATAAAACTGATGCTTACCGAGTCTTTGAGAAAAAACTAAAGA
AAGGTCATCCACCTAAAAATTGGAATGATTTATTTAGTGACTGTATAAATGAAGCTGACTGTCAGGATCCTTAA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12338.70 Da        Isoelectric Point: 4.1654

>AT86535 WP_098941858.1 NZ_CP023965:c1464342-1464007 [Proteus vulgaris]
MLTYVCTDNIALEADSKITERHQTTIPASIREALHLSGGDRIHYKLLSTGDVLISRHSDGSEDPVMASFLNFLAQDITNH
PQTIQPLDISRGFELVEGMDINLDDDITDNE

Download         Length: 336 bp

>AT86535 NZ_CP023965:c1464342-1464007 [Proteus vulgaris]
ATGCTAACCTACGTTTGCACTGACAACATCGCTCTTGAAGCTGATTCAAAAATAACAGAACGTCATCAAACCACAATTCC
CGCGTCAATTAGAGAAGCTCTACATCTTAGTGGTGGAGATCGTATTCACTACAAATTACTAAGCACTGGTGATGTACTTA
TCTCACGTCACAGCGATGGATCTGAAGATCCTGTTATGGCATCGTTTCTTAATTTTCTCGCTCAAGATATAACTAATCAT
CCTCAAACCATTCAACCTCTCGATATATCTCGTGGTTTTGAATTAGTTGAAGGTATGGATATCAACCTTGACGATGACAT
CACCGATAACGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References