86001

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 3773517..3774036 Replicon chromosome
Accession NZ_CP023778
Organism Nocardia terpenica strain NC_YFY_NT001

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag CRH09_RS16815 Protein ID WP_098694740.1
Coordinates 3773767..3774036 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag CRH09_RS16810 Protein ID WP_098694739.1
Coordinates 3773517..3773774 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CRH09_RS16785 3769422..3770399 - 978 WP_098694734.1 zinc-binding dehydrogenase -
CRH09_RS16790 3770530..3771159 + 630 WP_098694735.1 urease accessory protein UreF -
CRH09_RS16795 3771176..3771877 + 702 WP_098694736.1 urease accessory protein UreG -
CRH09_RS16800 3771867..3772517 + 651 WP_098694737.1 urease accessory protein UreD -
CRH09_RS16805 3772595..3773206 + 612 WP_198407426.1 Uma2 family endonuclease -
CRH09_RS40660 3773241..3773417 - 177 WP_157777544.1 hypothetical protein -
CRH09_RS16810 3773517..3773774 + 258 WP_098694739.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CRH09_RS16815 3773767..3774036 + 270 WP_098694740.1 Txe/YoeB family addiction module toxin Toxin
CRH09_RS16820 3774066..3774347 - 282 WP_098694741.1 hypothetical protein -
CRH09_RS16825 3774568..3775347 - 780 WP_098694742.1 DUF456 domain-containing protein -
CRH09_RS16830 3775601..3777031 - 1431 WP_098694743.1 NAD(P)/FAD-dependent oxidoreductase -
CRH09_RS16835 3777294..3777977 - 684 WP_157777545.1 TetR/AcrR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-67)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10183.60 Da        Isoelectric Point: 9.4594

>T86001 WP_098694740.1 NZ_CP023778:3773767-3774036 [Nocardia terpenica]
MTDRKLTFTAYGWETYTSWLARDRTVLKAANKVINAALTDPFSGIGKPEPLRHQLAGNWSRRITREHRLVYYVTDTELVI
VAVGGHYCD

Download         Length: 270 bp

>T86001 NZ_CP023778:3773767-3774036 [Nocardia terpenica]
ATGACTGATCGCAAACTCACCTTCACCGCATACGGCTGGGAAACTTACACGTCCTGGCTCGCCCGCGACCGCACGGTCCT
GAAGGCCGCGAACAAGGTGATCAACGCCGCCTTGACCGACCCGTTCTCCGGAATCGGAAAGCCCGAGCCGCTCCGACATC
AACTGGCGGGCAATTGGTCGCGCCGCATCACCCGTGAGCATCGCTTGGTCTACTACGTCACGGACACCGAACTCGTCATC
GTCGCCGTCGGCGGCCACTACTGCGACTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9184.13 Da        Isoelectric Point: 4.0917

>AT86001 WP_098694739.1 NZ_CP023778:3773517-3773774 [Nocardia terpenica]
MPALPISTVRQNLFGLVQQVNDDHDTVTVVTKSGQNAVLVSEADWNSIQETLYVLATHGGVELLESARAARNGETTAHEL
IDPDD

Download         Length: 258 bp

>AT86001 NZ_CP023778:3773517-3773774 [Nocardia terpenica]
ATGCCTGCACTACCCATCTCCACCGTCCGCCAGAACCTGTTCGGTTTGGTGCAGCAGGTCAACGACGACCACGACACGGT
CACCGTGGTGACGAAGTCGGGGCAGAATGCGGTGCTGGTGTCGGAGGCCGACTGGAACTCCATCCAGGAGACGCTGTATG
TCCTGGCGACGCACGGCGGCGTCGAACTGCTCGAATCCGCTCGCGCGGCGCGCAATGGCGAAACGACAGCGCACGAGCTG
ATCGATCCCGATGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References