Detailed information of TA system TA085897

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): DinJ-YafQ (relBE)/YafQ-RelB
• Location: 18307..18835
• Replicon: plasmid pZM36
• Accession: NZ_CP023680
• Organism: Zymomonas mobilis subsp. mobilis strain ZM4 substr. 2032

Toxin (Protein)

• Gene name: yafQ
• Uniprot ID: -
• Locus tag: ZMO2_RS09730
• Protein ID: WP_062339761.1
• Coordinates: 18307..18576 (-)
• Length: 90 a.a.

Antitoxin (Protein)

• Gene name: dinJ
• Uniprot ID: -
• Locus tag: ZMO2_RS09735
• Protein ID: WP_062339759.1
• Coordinates: 18578..18835 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ZMO2_RS09685	13785..14768	+	984	WP_062339740.1	hypothetical protein	-
ZMO2_RS09695	15092..15454	-	363	WP_108125223.1	hypothetical protein	-
ZMO2_RS09700	15990..16229	-	240	WP_062339772.1	hypothetical protein	-
ZMO2_RS09705	16240..16428	-	189	WP_062339770.1	hypothetical protein	-
ZMO2_RS09715	16907..17233	-	327	WP_062339766.1	hypothetical protein	-
ZMO2_RS09720	17338..17664	-	327	WP_062339764.1	hypothetical protein	-
ZMO2_RS09725	17693..18055	-	363	WP_151457906.1	hypothetical protein	-
ZMO2_RS09730	18307..18576	-	270	WP_062339761.1	type II toxin-antitoxin system YafQ family toxin	Toxin
ZMO2_RS09735	18578..18835	-	258	WP_062339759.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
ZMO2_RS09740	19249..20517	+	1269	WP_081094489.1	DNA damage-inducible protein D	-
ZMO2_RS09745	20764..21645	+	882	WP_108125225.1	hypothetical protein	-
ZMO2_RS09750	21716..21970	-	255	WP_062339701.1	hypothetical protein	-
ZMO2_RS09755	21976..22437	-	462	WP_063630121.1	helix-turn-helix domain-containing protein	-
ZMO2_RS09760	22451..22786	-	336	WP_081094484.1	type II toxin-antitoxin system RelE/ParE family toxin	-
ZMO2_RS09765	23033..23503	-	471	WP_062339703.1	helix-turn-helix domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..36494	36494

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (6-89)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-84)

Sequences

Toxin

Protein

• Length: 90 a.a.
• Molecular weight: 10398.16 Da
• Isoelectric Point: 10.0220

>T85897 WP_062339761.1 NZ_CP023680:c18576-18307 [Zymomonas mobilis subsp. mobilis]
VLTPIRSSKFKKDIKKLQKRGKDMEKLKKAILYLINEQALPPAYRSHVLSGDWSGYYDLHLEPDWLLLYKIADMELHLAR
TGSHSDVFK

Nucleotide

• Length: 270 bp

>T85897 NZ_CP023680:c18576-18307 [Zymomonas mobilis subsp. mobilis]
GTGCTAACGCCTATCCGATCGAGCAAATTCAAGAAAGACATAAAAAAATTACAGAAGCGAGGTAAGGATATGGAAAAATT
AAAAAAAGCCATTCTTTACCTGATTAATGAACAAGCCTTACCACCAGCCTACCGAAGCCATGTTTTAAGTGGCGATTGGT
CGGGTTACTACGATTTGCATTTGGAACCTGACTGGCTCCTGCTCTATAAAATAGCTGATATGGAATTGCATCTAGCGCGA
ACAGGCAGCCATTCAGATGTTTTTAAGTGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9372.01 Da
• Isoelectric Point: 8.6589

>AT85897 WP_062339759.1 NZ_CP023680:c18835-18578 [Zymomonas mobilis subsp. mobilis]
MKADSVVRARIPTLTKEAAIKTLEQMGLSISDAIRLLMTKIANEQRLPFSVELPTVETKKAIIELENGKGKTFKNADALF
EDLGI

Nucleotide

• Length: 258 bp

>AT85897 NZ_CP023680:c18835-18578 [Zymomonas mobilis subsp. mobilis]
ATGAAAGCAGATTCTGTTGTTAGAGCACGCATCCCAACCTTGACCAAGGAAGCCGCGATTAAAACTTTGGAGCAGATGGG
ACTTAGTATTTCTGATGCTATCCGGTTGCTTATGACTAAAATCGCCAATGAGCAACGTCTTCCCTTTTCTGTTGAATTAC
CAACGGTGGAAACCAAAAAAGCGATTATCGAATTGGAAAATGGAAAAGGTAAGACTTTTAAAAATGCAGATGCTCTGTTC
GAGGATTTAGGTATTTAA