85834

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 407..948 Replicon plasmid pApBDGP5C
Accession NZ_CP023660
Organism Acetobacter pomorum strain BDGP5

Toxin (Protein)


Gene name yoeB Uniprot ID A0A252ELZ7
Locus tag CPF11_RS14175 Protein ID WP_039891754.1
Coordinates 407..676 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID F1YTL2
Locus tag CPF11_RS14180 Protein ID WP_006116374.1
Coordinates 673..948 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CPF11_RS14175 407..676 - 270 WP_039891754.1 Txe/YoeB family addiction module toxin Toxin
CPF11_RS14180 673..948 - 276 WP_006116374.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
CPF11_RS14625 1774..1947 + 174 WP_157884551.1 hypothetical protein -
CPF11_RS14185 2296..2670 + 375 WP_139018868.1 hypothetical protein -
CPF11_RS14190 2684..3016 + 333 WP_081461445.1 hypothetical protein -
CPF11_RS14195 3072..3476 - 405 WP_006116376.1 DUF2442 domain-containing protein -
CPF11_RS14200 3789..4211 - 423 WP_039891761.1 type II toxin-antitoxin system VapC family toxin -
CPF11_RS14205 4208..4453 - 246 WP_170315311.1 plasmid stabilization protein -
CPF11_RS14210 4564..4818 - 255 WP_081461446.1 hypothetical protein -
CPF11_RS14215 4903..5145 - 243 WP_170315312.1 BrnA antitoxin family protein -
CPF11_RS14220 5156..5332 - 177 Protein_12 BrnT family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..19216 19216


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-75)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10660.00 Da        Isoelectric Point: 6.9785

>T85834 WP_039891754.1 NZ_CP023660:c676-407 [Acetobacter pomorum]
VTVVFHEDGWEDYLSWFRSDHAVLEKINALIEDVRRHPFQGLGKPEPLKGQLSGWWSRRITGEHRLVYRVQGRVEEDQRI
EVAQCRFHY

Download         Length: 270 bp

>T85834 NZ_CP023660:c676-407 [Acetobacter pomorum]
GTGACAGTCGTTTTTCATGAAGATGGCTGGGAGGATTATCTTTCGTGGTTCCGCTCAGACCATGCGGTTCTTGAGAAGAT
CAATGCCCTGATTGAGGATGTAAGGCGGCATCCGTTTCAGGGGCTGGGCAAGCCGGAACCGCTGAAAGGTCAGCTTTCCG
GGTGGTGGTCTCGTCGGATTACGGGAGAACATCGTCTGGTCTACCGGGTTCAGGGGCGTGTGGAGGAGGATCAGCGGATT
GAGGTCGCACAGTGTCGGTTTCATTACTGA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10224.36 Da        Isoelectric Point: 4.8562

>AT85834 WP_006116374.1 NZ_CP023660:c948-673 [Acetobacter pomorum]
MTCVSYTDLRQNLAHYLDEAVNSRAPIVVTRKTGKGSVVLMSEEEFSGWQETVHLLSSPRNAERLLRSIRDIEHGTATEH
DLLEPQGESSE

Download         Length: 276 bp

>AT85834 NZ_CP023660:c948-673 [Acetobacter pomorum]
ATGACCTGTGTTTCCTATACCGACTTGCGCCAGAACCTGGCGCATTATCTGGACGAAGCCGTGAACAGCCGCGCGCCGAT
TGTCGTGACCCGCAAGACCGGGAAAGGCAGTGTCGTGCTGATGTCGGAAGAAGAATTCTCCGGCTGGCAGGAGACCGTGC
ATCTCCTGAGCAGCCCGCGCAACGCGGAGAGGCTGTTGCGGAGTATCCGAGACATTGAGCACGGGACCGCGACCGAGCAT
GATCTTCTGGAGCCGCAGGGTGAATCGTCAGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A252ELZ7

Antitoxin

Source ID Structure
AlphaFold DB A0A252ELY2

References