Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/HTH(antitoxin) |
Location | 2548615..2549264 | Replicon | chromosome |
Accession | NZ_CP023641 | ||
Organism | Pseudomonas mendocina strain MAE1-K |
Toxin (Protein)
Gene name | higB | Uniprot ID | - |
Locus tag | CO724_RS12115 | Protein ID | WP_047588122.1 |
Coordinates | 2548920..2549264 (-) | Length | 115 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | A0A396RZ86 |
Locus tag | CO724_RS12110 | Protein ID | WP_014596891.1 |
Coordinates | 2548615..2548923 (-) | Length | 103 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CO724_RS12095 | 2544374..2545480 | + | 1107 | WP_096826295.1 | trypsin-like peptidase domain-containing protein | - |
CO724_RS12100 | 2545616..2546596 | - | 981 | WP_096825341.1 | IS5-like element ISPst5 family transposase | - |
CO724_RS12105 | 2547359..2548228 | + | 870 | WP_014596892.1 | LysR family transcriptional regulator | - |
CO724_RS12110 | 2548615..2548923 | - | 309 | WP_014596891.1 | transcriptional regulator | Antitoxin |
CO724_RS12115 | 2548920..2549264 | - | 345 | WP_047588122.1 | toxin | Toxin |
CO724_RS12120 | 2549422..2550349 | - | 928 | Protein_2406 | LysR family transcriptional regulator | - |
CO724_RS12125 | 2550363..2551562 | - | 1200 | WP_096826296.1 | MFS transporter | - |
CO724_RS12130 | 2551647..2553500 | - | 1854 | WP_096826297.1 | asparagine synthase (glutamine-hydrolyzing) | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Integrative and Conjugative Element | - | - | 2506535..2578602 | 72067 | |
- | flank | IS/Tn | - | - | 2545616..2546596 | 980 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 115 a.a. Molecular weight: 13366.33 Da Isoelectric Point: 10.2892
>T85799 WP_047588122.1 NZ_CP023641:c2549264-2548920 [Pseudomonas mendocina]
MKALFVELSPFERNRKAHLDDDEYSLFQQMLLTNPEAGAVIANSGGLRKVRFGSVRRNKGKRGGVRVIYYYWLRGLQFWL
FTLYDKDELDDLSSDQRRQLKALLEREVKARQAP
MKALFVELSPFERNRKAHLDDDEYSLFQQMLLTNPEAGAVIANSGGLRKVRFGSVRRNKGKRGGVRVIYYYWLRGLQFWL
FTLYDKDELDDLSSDQRRQLKALLEREVKARQAP
Download Length: 345 bp
>T85799 NZ_CP023641:c2549264-2548920 [Pseudomonas mendocina]
ATGAAAGCATTGTTTGTTGAACTGTCACCCTTTGAACGCAACCGAAAAGCCCACCTCGATGATGACGAGTACTCGCTATT
CCAGCAGATGCTCTTGACCAACCCGGAGGCAGGCGCAGTCATCGCCAACAGCGGTGGTCTGAGGAAAGTCCGATTCGGAT
CGGTCAGGCGCAACAAGGGGAAGCGAGGTGGCGTTCGGGTGATTTACTACTACTGGCTCCGCGGTCTGCAGTTCTGGCTC
TTCACCCTGTATGACAAAGACGAACTCGATGACCTGAGCAGTGACCAGCGTAGGCAGCTGAAAGCGCTCCTTGAGCGCGA
AGTGAAGGCGAGGCAAGCACCATGA
ATGAAAGCATTGTTTGTTGAACTGTCACCCTTTGAACGCAACCGAAAAGCCCACCTCGATGATGACGAGTACTCGCTATT
CCAGCAGATGCTCTTGACCAACCCGGAGGCAGGCGCAGTCATCGCCAACAGCGGTGGTCTGAGGAAAGTCCGATTCGGAT
CGGTCAGGCGCAACAAGGGGAAGCGAGGTGGCGTTCGGGTGATTTACTACTACTGGCTCCGCGGTCTGCAGTTCTGGCTC
TTCACCCTGTATGACAAAGACGAACTCGATGACCTGAGCAGTGACCAGCGTAGGCAGCTGAAAGCGCTCCTTGAGCGCGA
AGTGAAGGCGAGGCAAGCACCATGA
Antitoxin
Download Length: 103 a.a. Molecular weight: 11561.34 Da Isoelectric Point: 10.0927
>AT85799 WP_014596891.1 NZ_CP023641:c2548923-2548615 [Pseudomonas mendocina]
MTKRDIFSELIEGFDDLAAAREGKRTLRTHKVEYTPIEPATGAEIVALREKLKMSQGVFAQAIHAKPATLKNWEQNRSKP
NDQATVLIRILNKHPDLIRELA
MTKRDIFSELIEGFDDLAAAREGKRTLRTHKVEYTPIEPATGAEIVALREKLKMSQGVFAQAIHAKPATLKNWEQNRSKP
NDQATVLIRILNKHPDLIRELA
Download Length: 309 bp
>AT85799 NZ_CP023641:c2548923-2548615 [Pseudomonas mendocina]
ATGACCAAACGCGATATTTTTTCCGAGCTGATCGAAGGCTTCGACGACCTGGCCGCAGCACGTGAAGGCAAGCGTACGCT
GCGTACCCACAAGGTCGAATACACGCCAATCGAGCCCGCGACAGGCGCGGAAATCGTCGCACTGCGCGAAAAGCTGAAGA
TGTCTCAGGGTGTATTCGCCCAGGCCATTCACGCCAAGCCAGCGACTCTCAAAAACTGGGAACAGAACCGCTCAAAGCCC
AACGACCAGGCTACTGTTCTCATCCGTATCCTGAACAAGCATCCGGACCTCATACGCGAACTGGCGTAG
ATGACCAAACGCGATATTTTTTCCGAGCTGATCGAAGGCTTCGACGACCTGGCCGCAGCACGTGAAGGCAAGCGTACGCT
GCGTACCCACAAGGTCGAATACACGCCAATCGAGCCCGCGACAGGCGCGGAAATCGTCGCACTGCGCGAAAAGCTGAAGA
TGTCTCAGGGTGTATTCGCCCAGGCCATTCACGCCAAGCCAGCGACTCTCAAAAACTGGGAACAGAACCGCTCAAAGCCC
AACGACCAGGCTACTGTTCTCATCCGTATCCTGAACAAGCATCCGGACCTCATACGCGAACTGGCGTAG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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