Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 2148318..2148500 Replicon chromosome
Accession NZ_CP023561
Organism Staphylococcus aureus strain TF3198

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag CPC18_RS10785 Protein ID WP_001801861.1
Coordinates 2148318..2148413 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2148441..2148500 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CPC18_RS10735 2143978..2144604 + 627 WP_000669046.1 hypothetical protein -
CPC18_RS10740 2144645..2144989 + 345 WP_000627551.1 DUF3969 family protein -
CPC18_RS10745 2145087..2145638 + 552 WP_000414205.1 hypothetical protein -
CPC18_RS10750 2145856..2146497 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
CPC18_RS10755 2146611..2146796 - 186 WP_000809857.1 hypothetical protein -
CPC18_RS10760 2146798..2146974 - 177 WP_000375476.1 hypothetical protein -
CPC18_RS10765 2146985..2147368 - 384 WP_000070811.1 hypothetical protein -
CPC18_RS10775 2147972..2148115 - 144 WP_001549059.1 transposase -
CPC18_RS10785 2148318..2148413 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 2148441..2148500 - 60 - - Antitoxin
CPC18_RS10790 2148536..2148637 + 102 WP_001791893.1 hypothetical protein -
CPC18_RS10795 2148615..2148791 - 177 Protein_2037 transposase -
CPC18_RS10800 2148985..2149362 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2141418..2167015 25597


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T81618 WP_001801861.1 NZ_CP023561:2148318-2148413 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T81618 NZ_CP023561:2148318-2148413 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT81618 NZ_CP023561:c2148500-2148441 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References