Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1906797..1907014 Replicon chromosome
Accession NZ_CP023500
Organism Staphylococcus aureus strain FDAARGOS_412

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag CO684_RS10085 Protein ID WP_001802298.1
Coordinates 1906910..1907014 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 1906797..1906852 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CO684_RS10065 1903000..1903665 - 666 WP_001024094.1 SDR family oxidoreductase -
CO684_RS10070 1903817..1904137 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
CO684_RS10075 1904139..1905119 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
CO684_RS10080 1905385..1906476 + 1092 WP_000495671.1 lytic regulatory protein -
- 1906797..1906852 + 56 - - Antitoxin
CO684_RS10085 1906910..1907014 - 105 WP_001802298.1 hypothetical protein Toxin
CO684_RS14420 1907175..1907658 - 484 Protein_1864 recombinase family protein -
CO684_RS10095 1907701..1908837 - 1137 WP_000115564.1 SAP domain-containing protein -
CO684_RS10100 1909126..1909218 + 93 WP_001790138.1 hypothetical protein -
CO684_RS10105 1909923..1910780 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
CO684_RS10110 1910848..1911630 - 783 WP_000908177.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T81407 WP_001802298.1 NZ_CP023500:c1907014-1906910 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T81407 NZ_CP023500:c1907014-1906910 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT81407 NZ_CP023500:1906797-1906852 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References