Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1569921..1570103 Replicon chromosome
Accession NZ_CP023500
Organism Staphylococcus aureus strain FDAARGOS_412

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag CO684_RS14405 Protein ID WP_001801861.1
Coordinates 1569921..1570016 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1570044..1570103 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CO684_RS07965 1565581..1566207 + 627 WP_000669046.1 hypothetical protein -
CO684_RS07970 1566248..1566592 + 345 WP_000627551.1 DUF3969 family protein -
CO684_RS07975 1566690..1567241 + 552 WP_000414205.1 hypothetical protein -
CO684_RS07980 1567459..1568100 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
CO684_RS07985 1568214..1568399 - 186 WP_000809857.1 hypothetical protein -
CO684_RS07990 1568401..1568577 - 177 WP_000375476.1 hypothetical protein -
CO684_RS07995 1568588..1568971 - 384 WP_000070811.1 hypothetical protein -
CO684_RS08005 1569575..1569718 - 144 WP_001549059.1 transposase -
CO684_RS14405 1569921..1570016 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1570044..1570103 - 60 - - Antitoxin
CO684_RS08010 1570139..1570240 + 102 WP_001791893.1 hypothetical protein -
CO684_RS08015 1570218..1570394 - 177 Protein_1513 transposase -
CO684_RS08020 1570588..1570965 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - lukD / hlgA 1532481..1618514 86033


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T81396 WP_001801861.1 NZ_CP023500:1569921-1570016 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T81396 NZ_CP023500:1569921-1570016 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT81396 NZ_CP023500:c1570103-1570044 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References