Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 2398936..2399590 Replicon chromosome
Accession NZ_CP023466
Organism Pseudomonas frederiksbergensis strain KNU-15

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag CNN82_RS11205 Protein ID WP_096481610.1
Coordinates 2399240..2399590 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag CNN82_RS11200 Protein ID WP_007940887.1
Coordinates 2398936..2399250 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CNN82_RS11180 2395916..2396116 + 201 WP_028941258.1 hypothetical protein -
CNN82_RS11185 2396195..2396527 + 333 WP_096479910.1 DUF2790 domain-containing protein -
CNN82_RS11190 2396897..2397277 + 381 WP_028941260.1 hypothetical protein -
CNN82_RS11195 2397434..2398759 - 1326 WP_096479911.1 OprD family porin -
CNN82_RS11200 2398936..2399250 - 315 WP_007940887.1 transcriptional regulator Antitoxin
CNN82_RS11205 2399240..2399590 - 351 WP_096481610.1 toxin Toxin
CNN82_RS11210 2399965..2400429 + 465 WP_019580069.1 GNAT family N-acetyltransferase -
CNN82_RS11215 2400521..2401399 - 879 WP_026331776.1 alpha/beta fold hydrolase -
CNN82_RS11220 2401396..2402358 - 963 WP_096479912.1 class I SAM-dependent methyltransferase -
CNN82_RS11225 2402355..2403590 - 1236 WP_096479913.1 YcaO-like family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-100)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 14074.86 Da        Isoelectric Point: 8.4119

>T81290 WP_096481610.1 NZ_CP023466:c2399590-2399240 [Pseudomonas frederiksbergensis]
MDALFIELPAFQKHRDDYLDDDLFRSFQLELLKNPEAGDLIEGTGRLRKIRFFDQRRGKGKRSGLRVIYYWWSGFDQFWL
FTVYSKNEQDDLSPSQKKLFRQTLDREINTRTHYET

Download         Length: 351 bp

>T81290 NZ_CP023466:c2399590-2399240 [Pseudomonas frederiksbergensis]
ATGGACGCTCTTTTTATCGAATTACCTGCGTTTCAGAAACACCGAGACGATTACCTGGATGACGATTTGTTCCGCAGCTT
TCAGTTGGAGCTGCTGAAAAACCCTGAAGCGGGCGATCTCATTGAAGGTACGGGCAGGCTGCGAAAAATCCGCTTTTTCG
ATCAACGTCGCGGTAAAGGCAAGCGTAGCGGGCTTAGGGTGATTTATTACTGGTGGTCAGGTTTCGATCAATTCTGGCTG
TTCACCGTGTATAGCAAAAACGAGCAAGACGACCTGTCGCCTTCCCAGAAAAAACTTTTCAGACAAACGCTGGATAGAGA
AATCAACACGAGAACCCACTATGAAACGTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11904.82 Da        Isoelectric Point: 10.3437

>AT81290 WP_007940887.1 NZ_CP023466:c2399250-2398936 [Pseudomonas frederiksbergensis]
MKRDIFSELMEGLEALADERQGKVTLRTHKVKLPKLVPITAEEVVAIRQQLNLSRSVFAMYLRTNTRTLENWEQGRATPN
AQATTLIRLVERFPQTIEQLAALT

Download         Length: 315 bp

>AT81290 NZ_CP023466:c2399250-2398936 [Pseudomonas frederiksbergensis]
ATGAAACGTGACATTTTTTCCGAACTGATGGAAGGCCTCGAAGCCTTGGCCGACGAGCGCCAAGGCAAGGTCACGCTGCG
GACCCACAAGGTCAAGCTGCCGAAACTGGTACCCATCACTGCCGAGGAAGTGGTAGCCATCCGTCAACAGCTCAATCTTT
CCCGGTCGGTGTTCGCCATGTATCTACGCACCAACACCCGAACCCTCGAAAACTGGGAACAAGGACGGGCAACACCAAAT
GCCCAAGCCACGACACTGATCCGCTTGGTTGAACGCTTTCCGCAAACAATCGAACAACTCGCAGCGCTGACCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References