Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yefM-yoeB (relBE)/YoeB-YefM |
Location | 4977765..4978272 | Replicon | chromosome |
Accession | NZ_CP023439 | ||
Organism | Thauera sp. K11 |
Toxin (Protein)
Gene name | yoeB | Uniprot ID | - |
Locus tag | CCZ27_RS21700 | Protein ID | WP_096451718.1 |
Coordinates | 4977765..4978019 (-) | Length | 85 a.a. |
Antitoxin (Protein)
Gene name | yefM | Uniprot ID | - |
Locus tag | CCZ27_RS21705 | Protein ID | WP_096451720.1 |
Coordinates | 4978000..4978272 (-) | Length | 91 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CCZ27_RS21680 | 4973144..4973560 | - | 417 | WP_096451710.1 | transcriptional repressor | - |
CCZ27_RS21685 | 4973672..4974670 | - | 999 | WP_198363220.1 | cytochrome-c peroxidase | - |
CCZ27_RS21690 | 4974957..4975847 | + | 891 | WP_096451714.1 | LysR family transcriptional regulator | - |
CCZ27_RS21695 | 4975863..4977527 | - | 1665 | WP_096451716.1 | thiamine pyrophosphate-binding protein | - |
CCZ27_RS21700 | 4977765..4978019 | - | 255 | WP_096451718.1 | Txe/YoeB family addiction module toxin | Toxin |
CCZ27_RS21705 | 4978000..4978272 | - | 273 | WP_096451720.1 | type II toxin-antitoxin system prevent-host-death family antitoxin | Antitoxin |
CCZ27_RS21710 | 4978312..4979735 | + | 1424 | Protein_4338 | integrase family protein | - |
CCZ27_RS21715 | 4979775..4980116 | + | 342 | WP_096451722.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
CCZ27_RS21720 | 4980113..4980400 | + | 288 | WP_096451724.1 | helix-turn-helix domain-containing protein | - |
CCZ27_RS21730 | 4981239..4981787 | - | 549 | WP_096451726.1 | crossover junction endodeoxyribonuclease RuvC | - |
CCZ27_RS21735 | 4981800..4982117 | - | 318 | WP_096451728.1 | heavy metal-binding domain-containing protein | - |
CCZ27_RS21740 | 4982200..4982925 | - | 726 | WP_096451730.1 | YebC/PmpR family DNA-binding transcriptional regulator | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 85 a.a. Molecular weight: 10184.52 Da Isoelectric Point: 8.1110
>T81275 WP_096451718.1 NZ_CP023439:c4978019-4977765 [Thauera sp. K11]
MPLKFADHAWDDYVYWSQHDRKVLKRINQLIEDIRRHPFEGIGKPEPLKHQLSGFWSRRTDDRHRLVYAINGDDVLIAQC
RDHY
MPLKFADHAWDDYVYWSQHDRKVLKRINQLIEDIRRHPFEGIGKPEPLKHQLSGFWSRRTDDRHRLVYAINGDDVLIAQC
RDHY
Download Length: 255 bp
>T81275 NZ_CP023439:c4978019-4977765 [Thauera sp. K11]
ATGCCGCTGAAGTTCGCTGACCATGCGTGGGACGACTACGTCTATTGGAGCCAGCATGACCGCAAAGTCCTCAAGCGCAT
CAACCAACTGATCGAGGACATCCGGCGGCACCCCTTCGAGGGGATCGGCAAACCGGAACCCCTGAAGCATCAGCTCTCGG
GGTTCTGGTCCCGCCGGACCGATGATCGTCATCGACTCGTGTATGCGATCAATGGCGACGACGTCTTGATCGCGCAGTGC
CGGGACCACTATTGA
ATGCCGCTGAAGTTCGCTGACCATGCGTGGGACGACTACGTCTATTGGAGCCAGCATGACCGCAAAGTCCTCAAGCGCAT
CAACCAACTGATCGAGGACATCCGGCGGCACCCCTTCGAGGGGATCGGCAAACCGGAACCCCTGAAGCATCAGCTCTCGG
GGTTCTGGTCCCGCCGGACCGATGATCGTCATCGACTCGTGTATGCGATCAATGGCGACGACGTCTTGATCGCGCAGTGC
CGGGACCACTATTGA
Antitoxin
Download Length: 91 a.a. Molecular weight: 10027.30 Da Isoelectric Point: 4.8182
>AT81275 WP_096451720.1 NZ_CP023439:c4978272-4978000 [Thauera sp. K11]
MDALTFSYTRAHLAEVMRTVNEDRAPVLVTTQRGKPVVIMSLDDYNALEETAYLLRNPKGARRLLDSVEQLRAGSGSVHE
PIDDDAAEVR
MDALTFSYTRAHLAEVMRTVNEDRAPVLVTTQRGKPVVIMSLDDYNALEETAYLLRNPKGARRLLDSVEQLRAGSGSVHE
PIDDDAAEVR
Download Length: 273 bp
>AT81275 NZ_CP023439:c4978272-4978000 [Thauera sp. K11]
ATGGACGCCCTGACCTTCAGCTACACGCGAGCCCACCTCGCCGAGGTGATGCGCACCGTCAACGAGGACCGCGCGCCCGT
ACTCGTCACCACTCAACGCGGCAAGCCGGTGGTCATCATGTCGCTCGACGACTACAACGCCCTCGAAGAAACCGCATACC
TGCTGCGCAACCCCAAGGGCGCCCGCCGCTTGCTCGATTCGGTCGAACAGCTTCGTGCCGGCAGCGGCTCCGTGCATGAA
CCGATCGACGACGATGCCGCTGAAGTTCGCTGA
ATGGACGCCCTGACCTTCAGCTACACGCGAGCCCACCTCGCCGAGGTGATGCGCACCGTCAACGAGGACCGCGCGCCCGT
ACTCGTCACCACTCAACGCGGCAAGCCGGTGGTCATCATGTCGCTCGACGACTACAACGCCCTCGAAGAAACCGCATACC
TGCTGCGCAACCCCAAGGGCGCCCGCCGCTTGCTCGATTCGGTCGAACAGCTTCGTGCCGGCAGCGGCTCCGTGCATGAA
CCGATCGACGACGATGCCGCTGAAGTTCGCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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