Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HTH(antitoxin)
Location 2874800..2875421 Replicon chromosome
Accession NZ_CP023415
Organism Desulfovibrio sp. G11

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag CNY67_RS13030 Protein ID WP_197971537.1
Coordinates 2875191..2875421 (-) Length 77 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag CNY67_RS13025 Protein ID WP_072312240.1
Coordinates 2874800..2875048 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CNY67_RS13010 2871035..2872534 - 1500 WP_096152730.1 phosphomannomutase -
CNY67_RS13015 2872807..2873508 + 702 WP_072312232.1 ERF family protein -
CNY67_RS13020 2873577..2874740 + 1164 WP_072312231.1 hypothetical protein -
CNY67_RS13025 2874800..2875048 - 249 WP_072312240.1 helix-turn-helix domain-containing protein Antitoxin
CNY67_RS13030 2875191..2875421 - 231 WP_197971537.1 DNA-binding protein Toxin
CNY67_RS13035 2875527..2876629 + 1103 Protein_2441 AAA family ATPase -
CNY67_RS13040 2876653..2876880 + 228 WP_072312229.1 WGR domain-containing protein -
CNY67_RS13045 2876890..2877927 + 1038 WP_096152731.1 DUF3150 domain-containing protein -
CNY67_RS13050 2877990..2878226 + 237 WP_072312227.1 hypothetical protein -
CNY67_RS13055 2878223..2878597 + 375 WP_072312226.1 type II toxin-antitoxin system death-on-curing family toxin -
CNY67_RS13060 2878661..2880364 + 1704 WP_072312225.1 VWA domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2841512..2932294 90782


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(24-68)


Sequences

Toxin        


Download         Length: 77 a.a.        Molecular weight: 8680.99 Da        Isoelectric Point: 9.2288

>T81227 WP_197971537.1 NZ_CP023415:c2875421-2875191 [Desulfovibrio sp. G11]
MFSEEQFLNFQWYLCQCPSAGDVIPETGGCRKIRWKVPGKGKRGGARVIYFLRTEAGQIVLVAAYSKNEREDVPRQ

Download         Length: 231 bp

>T81227 NZ_CP023415:c2875421-2875191 [Desulfovibrio sp. G11]
CTGTTTTCTGAAGAACAGTTTTTGAATTTCCAATGGTATCTTTGCCAATGTCCCAGTGCCGGGGATGTGATCCCGGAAAC
TGGAGGCTGTCGTAAAATCCGTTGGAAAGTACCGGGCAAGGGGAAAAGGGGTGGGGCAAGAGTCATTTATTTTTTGCGAA
CCGAGGCTGGGCAGATTGTCCTTGTGGCGGCCTATAGCAAGAATGAGCGTGAAGACGTGCCGCGCCAGTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9317.63 Da        Isoelectric Point: 7.2038

>AT81227 WP_072312240.1 NZ_CP023415:c2875048-2874800 [Desulfovibrio sp. G11]
MVDKNGVVISEETISNEQRLSLDARIRLGMSQQQFAKMLGISVRTLHDWEQGRREPSGAAKTLLYIAARHPDIVQEIVEQ
RT

Download         Length: 249 bp

>AT81227 NZ_CP023415:c2875048-2874800 [Desulfovibrio sp. G11]
ATGGTTGACAAGAACGGTGTTGTCATTTCTGAAGAAACAATTTCAAATGAACAACGCCTGTCTTTGGATGCCCGTATCAG
GCTGGGAATGTCCCAACAGCAGTTTGCCAAAATGCTGGGGATTTCTGTTCGCACCCTGCATGATTGGGAACAGGGAAGAC
GGGAGCCTTCAGGGGCTGCCAAGACCTTGCTCTATATTGCGGCACGACACCCTGATATTGTTCAGGAAATTGTGGAGCAG
CGTACTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References