Detailed information of TA system TA081215

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): yonT-as-bsrE/-
• Location: 2172888..2173105
• Replicon: chromosome
• Accession: NZ_CP023409
• Organism: Bacillus subtilis strain 7PJ-16

Toxin (Protein)

• Gene name: yonT
• Uniprot ID: -
• Locus tag: Bateq7PJ16_RS11630
• Protein ID: WP_019712271.1
• Coordinates: 2172888..2173064 (-)
• Length: 59 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2173005..2173105 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
Bateq7PJ16_RS11585	2168282..2168446	-	165	WP_159376880.1	hypothetical protein	-
Bateq7PJ16_RS11590	2168483..2168842	-	360	WP_159376881.1	hypothetical protein	-
Bateq7PJ16_RS11595	2168889..2169143	-	255	WP_159376882.1	hypothetical protein	-
Bateq7PJ16_RS11600	2169186..2169407	-	222	WP_159376883.1	hypothetical protein	-
Bateq7PJ16_RS11605	2169404..2169856	-	453	WP_159376884.1	hypothetical protein	-
Bateq7PJ16_RS11610	2170186..2171403	-	1218	WP_061891096.1	hypothetical protein	-
Bateq7PJ16_RS11615	2171422..2172268	-	847	Protein_2238	GIY-YIG nuclease family protein	-
Bateq7PJ16_RS11620	2172385..2172573	-	189	WP_003230987.1	hypothetical protein	-
Bateq7PJ16_RS11625	2172618..2172869	-	252	WP_159376885.1	hypothetical protein	-
Bateq7PJ16_RS11630	2172888..2173064	-	177	WP_019712271.1	hypothetical protein	Toxin
-	2173005..2173105	+	101	NuclAT_0	-	Antitoxin
-	2173005..2173105	+	101	NuclAT_0	-	Antitoxin
-	2173005..2173105	+	101	NuclAT_0	-	Antitoxin
-	2173005..2173105	+	101	NuclAT_0	-	Antitoxin
Bateq7PJ16_RS11635	2174018..2174212	+	195	WP_072692657.1	hypothetical protein	-
Bateq7PJ16_RS11640	2174252..2176126	+	1875	Protein_2243	hypothetical protein	-
Bateq7PJ16_RS11645	2176311..2177213	+	903	WP_061891092.1	GIY-YIG nuclease family protein	-
Bateq7PJ16_RS11650	2177434..2178060	+	627	WP_159376887.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2102251..2231315	129064

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 59 a.a.
• Molecular weight: 6864.42 Da
• Isoelectric Point: 12.8833

>T81215 WP_019712271.1 NZ_CP023409:c2173064-2172888 [Bacillus subtilis]
VLEKVGIIVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Nucleotide

• Length: 177 bp

>T81215 NZ_CP023409:c2173064-2172888 [Bacillus subtilis]
GTGCTTGAGAAAGTGGGTATCATAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGGTAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCCGATGA

Antitoxin

Nucleotide

• Length: 101 bp

>AT81215 NZ_CP023409:2173005-2173105 [Bacillus subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTATGATACCCACTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Structures

Antitoxin