Detailed information of TA system TA081132

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-rdlD/Ldr(toxin)
• Location: 341026..341248
• Replicon: chromosome
• Accession: NZ_CP023388
• Organism: Escherichia coli strain 1105

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: S1NWX0
• Locus tag: CNQ47_RS01795
• Protein ID: WP_001295224.1
• Coordinates: 341141..341248 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	rdlD
Locus tag	-
Coordinates	341026..341084 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CNQ47_RS01765	336467..337369	+	903	WP_000084677.1	dipeptide ABC transporter permease DppC	-
CNQ47_RS01770	337380..338363	+	984	WP_001196486.1	dipeptide ABC transporter ATP-binding protein	-
CNQ47_RS01775	338360..339364	+	1005	WP_000107018.1	dipeptide ABC transporter ATP-binding subunit DppF	-
CNQ47_RS01780	339394..340665	-	1272	WP_001313380.1	amino acid permease	-
-	341026..341084	-	59	-	-	Antitoxin
CNQ47_RS01795	341141..341248	+	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
CNQ47_RS01800	341334..343013	-	1680	WP_000191568.1	cellulose biosynthesis protein BcsG	-
CNQ47_RS01805	343010..343201	-	192	WP_000988308.1	cellulose biosynthesis protein BcsF	-
CNQ47_RS01810	343198..344769	-	1572	WP_077633450.1	cellulose biosynthesis protein BcsE	-
CNQ47_RS01815	345042..345230	+	189	WP_001063314.1	YhjR family protein	-
CNQ47_RS01820	345242..345994	+	753	WP_000279525.1	cellulose biosynthesis protein BcsQ	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3882.70 Da
• Isoelectric Point: 9.0157

>T81132 WP_001295224.1 NZ_CP023388:341141-341248 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Nucleotide

• Length: 108 bp

>T81132 NZ_CP023388:341141-341248 [Escherichia coli]
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAATAAGCGGAAGTAA

Antitoxin

Nucleotide

• Length: 59 bp

>AT81132 NZ_CP023388:c341084-341026 [Escherichia coli]
TCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Structures

Toxin

• AlphaFold DB: A0A4P7TSJ7

Antitoxin