Detailed information of TA system TA080865

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-rdlD/Ldr(toxin)
• Location: 219667..219889
• Replicon: chromosome
• Accession: NZ_CP023357
• Organism: Escherichia coli strain 317

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: S1NWX0
• Locus tag: CNQ55_RS01080
• Protein ID: WP_001295224.1
• Coordinates: 219782..219889 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	rdlD
Locus tag	-
Coordinates	219667..219733 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CNQ55_RS01050	215108..216010	+	903	WP_000084677.1	dipeptide ABC transporter permease DppC	-
CNQ55_RS01055	216021..217004	+	984	WP_001196477.1	dipeptide ABC transporter ATP-binding protein	-
CNQ55_RS01060	217001..218005	+	1005	WP_000103577.1	dipeptide ABC transporter ATP-binding subunit DppF	-
CNQ55_RS01065	218035..219306	-	1272	WP_001298005.1	amino acid permease	-
-	219667..219733	-	67	-	-	Antitoxin
CNQ55_RS01080	219782..219889	+	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
CNQ55_RS01085	219976..221655	-	1680	WP_000191565.1	cellulose biosynthesis protein BcsG	-
CNQ55_RS01090	221652..221843	-	192	WP_000988308.1	cellulose biosynthesis protein BcsF	-
CNQ55_RS01095	221840..223411	-	1572	WP_001204945.1	cellulose biosynthesis protein BcsE	-
CNQ55_RS01100	223684..223872	+	189	WP_001063314.1	YhjR family protein	-
CNQ55_RS01105	223884..224636	+	753	WP_000279536.1	cellulose biosynthesis protein BcsQ	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3882.70 Da
• Isoelectric Point: 9.0157

>T80865 WP_001295224.1 NZ_CP023357:219782-219889 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Nucleotide

• Length: 108 bp

>T80865 NZ_CP023357:219782-219889 [Escherichia coli]
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAATAAGCGGAAGTAA

Antitoxin

Nucleotide

• Length: 67 bp

>AT80865 NZ_CP023357:c219733-219667 [Escherichia coli]
GTCTAGGTTCAAGATTAGCCCCCGTGATATTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Structures

Toxin

• AlphaFold DB: A0A4P7TSJ7

Antitoxin