Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 1560393..1560904 Replicon chromosome
Accession NZ_CP023202
Organism Streptomyces xinghaiensis S187

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag SXIN_RS06580 Protein ID WP_019711099.1
Coordinates 1560393..1560647 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag SXIN_RS06585 Protein ID WP_019711100.1
Coordinates 1560644..1560904 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SXIN_RS06555 1555874..1556299 - 426 WP_192883558.1 cell division protein SepF -
SXIN_RS06560 1556436..1556699 + 264 WP_095756728.1 hypothetical protein -
SXIN_RS06565 1557035..1557670 - 636 WP_039823564.1 DUF4360 domain-containing protein -
SXIN_RS06570 1558143..1558487 - 345 WP_019711097.1 hypothetical protein -
SXIN_RS06575 1558956..1560176 - 1221 WP_039823574.1 transposase -
SXIN_RS06580 1560393..1560647 - 255 WP_019711099.1 Txe/YoeB family addiction module toxin Toxin
SXIN_RS06585 1560644..1560904 - 261 WP_019711100.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
SXIN_RS06590 1561366..1562178 + 813 WP_019711101.1 DedA family protein -
SXIN_RS06595 1562349..1563794 + 1446 WP_019711102.1 glyceraldehyde-3-phosphate dehydrogenase -
SXIN_RS06600 1564176..1564877 + 702 WP_095757953.1 phosphodiesterase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-70)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10088.37 Da        Isoelectric Point: 9.3930

>T80629 WP_019711099.1 NZ_CP023202:c1560647-1560393 [Streptomyces xinghaiensis S187]
VKTVFTEHGWADYVHWAETDRRMTRRINRLIEESKRDPFTGIGKPEPLKGDLSGYWSRRIDEEHRLVYRAKGDELVVVQA
RYHY

Download         Length: 255 bp

>T80629 NZ_CP023202:c1560647-1560393 [Streptomyces xinghaiensis S187]
GTGAAGACCGTATTCACCGAGCATGGTTGGGCCGACTACGTGCACTGGGCCGAGACGGACCGTCGCATGACCAGGCGCAT
CAATCGGCTCATCGAGGAGAGTAAGCGGGATCCGTTCACCGGCATCGGGAAGCCGGAGCCGCTCAAGGGGGATCTCAGCG
GCTACTGGTCCCGGAGGATCGATGAGGAGCACCGGCTCGTCTACCGGGCCAAAGGTGACGAACTCGTCGTCGTCCAGGCG
CGGTACCACTACTGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9624.58 Da        Isoelectric Point: 4.3246

>AT80629 WP_019711100.1 NZ_CP023202:c1560904-1560644 [Streptomyces xinghaiensis S187]
VSITASEARKNLFRLIENVNDDRSPVHITSRNGNAVLLSEEDFASWQETIYLLRSPANARRLAESIAEAEGGRTEPRELI
EVDDAE

Download         Length: 261 bp

>AT80629 NZ_CP023202:c1560904-1560644 [Streptomyces xinghaiensis S187]
GTGTCCATCACCGCCAGTGAAGCCCGAAAGAATCTTTTCCGGTTGATCGAAAACGTCAACGACGATCGGTCTCCGGTGCA
CATCACTTCCCGTAACGGGAATGCCGTGCTGCTGTCCGAGGAGGACTTTGCCTCGTGGCAGGAGACGATCTACCTGCTGC
GGTCGCCGGCCAATGCCCGCCGGTTGGCTGAGTCGATCGCGGAAGCGGAGGGCGGCAGGACGGAGCCCCGAGAGCTGATC
GAGGTCGACGACGCCGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References