Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2421264..2421448 Replicon chromosome
Accession NZ_CP023076
Organism Staphylococcus argenteus strain XNO62

Toxin (Protein)


Gene name SprA2 Uniprot ID -
Locus tag CJ017_RS11970 Protein ID WP_000482653.1
Coordinates 2421341..2421448 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2421264..2421324 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CJ017_RS11955 2417116..2418849 - 1734 WP_031787186.1 ABC transporter ATP-binding protein/permease -
CJ017_RS11960 2418874..2420637 - 1764 WP_031787187.1 ABC transporter ATP-binding protein/permease -
- 2421264..2421324 + 61 - - Antitoxin
CJ017_RS11970 2421341..2421448 - 108 WP_000482653.1 type I toxin-antitoxin system Fst family toxin Toxin
CJ017_RS11975 2421582..2421968 - 387 WP_000779346.1 flippase GtxA -
CJ017_RS11980 2422236..2423378 + 1143 WP_100848602.1 glycerate kinase -
CJ017_RS11985 2423437..2424096 + 660 WP_000831306.1 membrane protein -
CJ017_RS11990 2424281..2425492 + 1212 WP_031787189.1 multidrug effflux MFS transporter -
CJ017_RS11995 2425608..2426087 - 480 WP_031787190.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sbi / hlgA / hlgA / hlgC / hlgB 2399061..2458109 59048


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4025.81 Da        Isoelectric Point: 11.0582

>T80470 WP_000482653.1 NZ_CP023076:c2421448-2421341 [Staphylococcus argenteus]
MFNLLINIMTTAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T80470 NZ_CP023076:c2421448-2421341 [Staphylococcus argenteus]
ATGTTCAATTTATTGATTAACATCATGACTACAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT80470 NZ_CP023076:2421264-2421324 [Staphylococcus argenteus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References