Detailed information of TA system TA080464

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1007838..1008085
• Replicon: chromosome
• Accession: NZ_CP023076
• Organism: Staphylococcus argenteus strain XNO62

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: CJ017_RS04960
• Protein ID: WP_031787354.1
• Coordinates: 1007838..1007945 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF2
Locus tag	-
Coordinates	1007940..1008085 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CJ017_RS04935	1004517..1005086	-	570	WP_000287261.1	competence protein ComK	-
CJ017_RS04940	1005296..1005514	+	219	WP_000876831.1	IDEAL domain-containing protein	-
CJ017_RS04945	1005595..1006581	-	987	WP_000668810.1	lipoate--protein ligase	-
CJ017_RS04950	1006776..1006952	+	177	WP_000214898.1	YkvS family protein	-
CJ017_RS04955	1006967..1007569	+	603	WP_031787353.1	CPBP family intramembrane metalloprotease	-
CJ017_RS04960	1007838..1007945	+	108	WP_031787354.1	putative holin-like toxin	Toxin
-	1007940..1008085	-	146	-	-	Antitoxin
CJ017_RS04965	1008580..1008861	+	282	Protein_946	lactococcin 972 family bacteriocin	-
CJ017_RS04970	1008905..1010869	+	1965	WP_031787355.1	bacteriocin-associated integral membrane family protein	-
CJ017_RS04975	1010872..1011192	+	321	WP_031787356.1	YxeA family protein	-
CJ017_RS04980	1011189..1011830	+	642	WP_031787357.1	ABC transporter ATP-binding protein	-
CJ017_RS04985	1011918..1012178	-	261	WP_169929182.1	hypothetical protein	-
CJ017_RS04990	1012493..1012780	+	288	WP_000410715.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3815.72 Da
• Isoelectric Point: 10.8004

>T80464 WP_031787354.1 NZ_CP023076:1007838-1007945 [Staphylococcus argenteus]
VISIANALHLMLSFGMFIVTFIGIVVAIININNKK

Nucleotide

• Length: 108 bp

>T80464 NZ_CP023076:1007838-1007945 [Staphylococcus argenteus]
GTGATATCTATTGCAAACGCATTACATTTAATGTTAAGTTTCGGTATGTTTATCGTAACTTTCATTGGTATAGTAGTCGC
AATAATTAATATAAACAATAAAAAATAA

Antitoxin

Nucleotide

• Length: 146 bp

>AT80464 NZ_CP023076:c1008085-1007940 [Staphylococcus argenteus]
AATTAAAAAAAGATATGTTACTATAAAAATGTAAAAAGACGACATGCAGGAACATGTCGCCTATTGAGCCCGTTAAAAAG
ACGGTGACTAAATGAGATTTTCTTTAACCATCATTCGTTGTCAAAGTTTTGAAATGATGGTTATTT

Structures

Antitoxin