Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 14378..14919 Replicon plasmid unnamed5
Accession NZ_CP023041
Organism Komagataeibacter saccharivorans strain CV1

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag CD178_RS17330 Protein ID WP_118963915.1
Coordinates 14378..14647 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag CD178_RS17335 Protein ID WP_110096482.1
Coordinates 14644..14919 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CD178_RS17315 9736..12444 - 2709 WP_118963912.1 class I SAM-dependent DNA methyltransferase -
CD178_RS17320 12484..13578 - 1095 WP_118963913.1 Fic family protein -
CD178_RS17325 13694..14365 - 672 WP_118963914.1 hypothetical protein -
CD178_RS17330 14378..14647 - 270 WP_118963915.1 Txe/YoeB family addiction module toxin Toxin
CD178_RS17335 14644..14919 - 276 WP_110096482.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
CD178_RS17340 14972..18058 - 3087 WP_118963932.1 Ti-type conjugative transfer relaxase TraA -
CD178_RS17345 18222..18515 + 294 WP_118963916.1 conjugal transfer protein TraD -
CD178_RS17350 18580..18843 + 264 WP_118963917.1 conjugal transfer protein TraD -
CD178_RS17355 18833..19207 + 375 WP_118963918.1 hypothetical protein -
CD178_RS17360 19222..19554 + 333 WP_118963919.1 hypothetical protein -
CD178_RS17365 19558..19815 + 258 WP_118963920.1 conjugal transfer protein TraD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..26645 26645


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-75)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10586.96 Da        Isoelectric Point: 8.1012

>T80361 WP_118963915.1 NZ_CP023041:c14647-14378 [Komagataeibacter saccharivorans]
VKVVFHEDGWEDYLSWFRSDHAVLEKVNALIEDVRRHPFQGLGKPEPLKGQLSGWWSRRITGEHRLVYRVQGRAGEDQRI
EIAQCRFHY

Download         Length: 270 bp

>T80361 NZ_CP023041:c14647-14378 [Komagataeibacter saccharivorans]
GTGAAAGTCGTTTTTCACGAAGATGGCTGGGAAGATTATCTTTCGTGGTTCCGGTCAGACCATGCGGTTCTTGAGAAGGT
CAATGCCCTGATCGAGGATGTAAGGCGGCATCCGTTTCAGGGGCTGGGCAAACCGGAACCACTGAAGGGGCAGCTTTCCG
GGTGGTGGTCCCGACGGATTACGGGAGAACATCGTCTGGTCTACCGGGTTCAGGGCCGCGCGGGGGAGGATCAGCGGATC
GAGATCGCCCAGTGCCGGTTTCATTACTGA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10165.38 Da        Isoelectric Point: 5.1213

>AT80361 WP_110096482.1 NZ_CP023041:c14919-14644 [Komagataeibacter saccharivorans]
MTCVSYTDLRQNLAHYLDEAVNSRAPIVVTRKTGKGSVVLMSEEEFSGWQETVHLLSSPRNAERLLRSIRDIEHGAATER
DLLEPQGEPSA

Download         Length: 276 bp

>AT80361 NZ_CP023041:c14919-14644 [Komagataeibacter saccharivorans]
ATGACCTGTGTTTCCTATACCGACCTGCGCCAGAACCTGGCGCATTATCTGGATGAAGCCGTAAACAGCCGCGCGCCGAT
TGTCGTGACCCGCAAGACCGGGAAAGGCAGTGTCGTGCTGATGTCGGAAGAAGAATTCTCAGGCTGGCAGGAAACCGTGC
ATCTCCTGAGCAGCCCGCGTAACGCGGAGAGGCTGTTGCGGAGCATTCGTGACATTGAGCACGGGGCGGCAACCGAGCGT
GATCTTCTGGAGCCGCAGGGCGAACCGTCGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References